Specificity protein 2 (Sp2) is essential for mouse development and autonomous proliferation of mouse embryonic fibroblasts.

Specificity protein 2 (Sp2) is essential for mouse development and autonomous proliferation of mouse embryonic fibroblasts.

BACKGROUND: The zinc finger protein Sp2 (specificity protein 2) is a member of the glutamine-rich Sp family of transcription factors. Despite its close similarity to Sp1, Sp3 and Sp4, Sp2 does not bind to DNA or activate transcription when expressed in mammalian cell lines. The expression pattern an...

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Bibliographic Details
Main Authors: Frank Baur, Kerstin Nau, Dennis Sadic, Lena Allweiss, Hans-Peter Elsässer, Nynke Gillemans, Ton de Wit, Imme Krüger, Marion Vollmer, Sjaak Philipsen, Guntram Suske
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2833205?pdf=render

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