Prominent 18F-FDG Uptake in the Adrenal Gland after Contralateral Adrenalectomy in a Known Case of Adrenocortical Oncocytic Carcinoma
Adrenocortical carcinoma (ACC) is a rare type of cancer that is associated with a high rate of recurrence and poor prognosis. The main diagnostic approaches to adrenocortical cancer include CT scan, MRI and the promising role of 18F-FDG PET/CT. The main therapeutic approaches include radical surgery...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Mashhad University of Medical Sciences
2023-06-01
|
| Series: | Asia Oceania Journal of Nuclear Medicine and Biology |
| Subjects: | |
| Online Access: | https://aojnmb.mums.ac.ir/article_21371_67140bb49868c787b5b874809eb88797.pdf |
| _version_ | 1797812742125518848 |
|---|---|
| author | Rakan Al-Rashdan Mohammed Aljaberi Ali Mohamedkhair Akram Al-Ibraheem |
| author_facet | Rakan Al-Rashdan Mohammed Aljaberi Ali Mohamedkhair Akram Al-Ibraheem |
| author_sort | Rakan Al-Rashdan |
| collection | DOAJ |
| description | Adrenocortical carcinoma (ACC) is a rare type of cancer that is associated with a high rate of recurrence and poor prognosis. The main diagnostic approaches to adrenocortical cancer include CT scan, MRI and the promising role of 18F-FDG PET/CT. The main therapeutic approaches include radical surgery of local disease and recurrences, as well as adjuvant mitotane therapy.The evaluation of adrenocortical carcinoma (ACC) could be difficult by using 18F-FDG PET/CT in view of the significant association between the 18F-FDG uptake and ACC. At the same time, not all adrenal glands with 18F-FDG uptake are considered to be malignant, so awareness of these various findings is substantial for ACC management, especially with limited data regarding the role of 18F-FDG PET/CT in ACC post-operative settings.This report discusses the case of a 47-year-old man with a history of left adrenocortical carcinoma who underwent adrenalectomy and received adjuvant mitotane therapy. 9 months after the surgery, a follow-up 18F-FDG PET/CT scan showed that the 18F-FDG uptake was prominent in the right adrenal gland without corresponding abnormal CT scan findings. |
| first_indexed | 2024-03-13T07:42:59Z |
| format | Article |
| id | doaj.art-93113ced626d475cb401b6dc36a3c347 |
| institution | Directory Open Access Journal |
| issn | 2322-5718 2322-5726 |
| language | English |
| last_indexed | 2024-03-13T07:42:59Z |
| publishDate | 2023-06-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Asia Oceania Journal of Nuclear Medicine and Biology |
| spelling | doaj.art-93113ced626d475cb401b6dc36a3c3472023-06-03T06:33:47ZengMashhad University of Medical SciencesAsia Oceania Journal of Nuclear Medicine and Biology2322-57182322-57262023-06-0111218118410.22038/aojnmb.2022.67950.147221371Prominent 18F-FDG Uptake in the Adrenal Gland after Contralateral Adrenalectomy in a Known Case of Adrenocortical Oncocytic CarcinomaRakan Al-Rashdan0Mohammed Aljaberi1Ali Mohamedkhair2Akram Al-Ibraheem3Department of Nuclear Medicine, King Hussein Cancer Center, Amman, JordanDepartment of Nuclear Medicine, King Hussein Cancer Center, Amman, JordanDepartment of Nuclear Medicine, King Hussein Cancer Center, Amman, JordanDepartment of Nuclear Medicine, King Hussein Cancer Center, Amman, JordanAdrenocortical carcinoma (ACC) is a rare type of cancer that is associated with a high rate of recurrence and poor prognosis. The main diagnostic approaches to adrenocortical cancer include CT scan, MRI and the promising role of 18F-FDG PET/CT. The main therapeutic approaches include radical surgery of local disease and recurrences, as well as adjuvant mitotane therapy.The evaluation of adrenocortical carcinoma (ACC) could be difficult by using 18F-FDG PET/CT in view of the significant association between the 18F-FDG uptake and ACC. At the same time, not all adrenal glands with 18F-FDG uptake are considered to be malignant, so awareness of these various findings is substantial for ACC management, especially with limited data regarding the role of 18F-FDG PET/CT in ACC post-operative settings.This report discusses the case of a 47-year-old man with a history of left adrenocortical carcinoma who underwent adrenalectomy and received adjuvant mitotane therapy. 9 months after the surgery, a follow-up 18F-FDG PET/CT scan showed that the 18F-FDG uptake was prominent in the right adrenal gland without corresponding abnormal CT scan findings.https://aojnmb.mums.ac.ir/article_21371_67140bb49868c787b5b874809eb88797.pdfadrenocortical carcinoma18f-fdg pet/ctmitotaneadrenalectomy |
| spellingShingle | Rakan Al-Rashdan Mohammed Aljaberi Ali Mohamedkhair Akram Al-Ibraheem Prominent 18F-FDG Uptake in the Adrenal Gland after Contralateral Adrenalectomy in a Known Case of Adrenocortical Oncocytic Carcinoma Asia Oceania Journal of Nuclear Medicine and Biology adrenocortical carcinoma 18f-fdg pet/ct mitotane adrenalectomy |
| title | Prominent 18F-FDG Uptake in the Adrenal Gland after Contralateral Adrenalectomy in a Known Case of Adrenocortical Oncocytic Carcinoma |
| title_full | Prominent 18F-FDG Uptake in the Adrenal Gland after Contralateral Adrenalectomy in a Known Case of Adrenocortical Oncocytic Carcinoma |
| title_fullStr | Prominent 18F-FDG Uptake in the Adrenal Gland after Contralateral Adrenalectomy in a Known Case of Adrenocortical Oncocytic Carcinoma |
| title_full_unstemmed | Prominent 18F-FDG Uptake in the Adrenal Gland after Contralateral Adrenalectomy in a Known Case of Adrenocortical Oncocytic Carcinoma |
| title_short | Prominent 18F-FDG Uptake in the Adrenal Gland after Contralateral Adrenalectomy in a Known Case of Adrenocortical Oncocytic Carcinoma |
| title_sort | prominent 18f fdg uptake in the adrenal gland after contralateral adrenalectomy in a known case of adrenocortical oncocytic carcinoma |
| topic | adrenocortical carcinoma 18f-fdg pet/ct mitotane adrenalectomy |
| url | https://aojnmb.mums.ac.ir/article_21371_67140bb49868c787b5b874809eb88797.pdf |
| work_keys_str_mv | AT rakanalrashdan prominent18ffdguptakeintheadrenalglandaftercontralateraladrenalectomyinaknowncaseofadrenocorticaloncocyticcarcinoma AT mohammedaljaberi prominent18ffdguptakeintheadrenalglandaftercontralateraladrenalectomyinaknowncaseofadrenocorticaloncocyticcarcinoma AT alimohamedkhair prominent18ffdguptakeintheadrenalglandaftercontralateraladrenalectomyinaknowncaseofadrenocorticaloncocyticcarcinoma AT akramalibraheem prominent18ffdguptakeintheadrenalglandaftercontralateraladrenalectomyinaknowncaseofadrenocorticaloncocyticcarcinoma |