Stabilization Control for a Class of Fractional-Order HIV-1 Infection Model with Time Delays

In this study, we investigated a novel asymptotic stabilization control method for a fractional-order HIV-1 infection model. First, we constructed a mathematical model of the fractional-order HIV-1 infection using the state-space equations of Caputo fractional calculus. Subsequently, a new control s...

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Main Authors: Zitong Li, Zhe Zhang
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Axioms
Subjects:
Online Access:https://www.mdpi.com/2075-1680/12/7/695
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author Zitong Li
Zhe Zhang
author_facet Zitong Li
Zhe Zhang
author_sort Zitong Li
collection DOAJ
description In this study, we investigated a novel asymptotic stabilization control method for a fractional-order HIV-1 infection model. First, we constructed a mathematical model of the fractional-order HIV-1 infection using the state-space equations of Caputo fractional calculus. Subsequently, a new control strategy was designed for the fractional-order HIV-1 infection model, and the corresponding asymptotic stabilization criterion was proposed by combining a novel vector Lyapunov function with the M-matrix method. Additionally, we incorporated a time delay, which was generated by the interaction between different variables in the actual system, into the fractional-order HIV-1 infection model, forming a system with a time delay. Based on the vector Lyapunov function associated with the M-matrix measure and Razumikhin interpretation, a control strategy was developed for the fractional-order HIV-1 infection model with a time delay. Finally, we show the results of two numerical simulations of the fractional-order HIV-1 infection model, with and without time delay, to illustrate the accuracy, usefulness, and universality of the proposed measure in our paper.
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spelling doaj.art-9312cf6f828542ee951c59a866da1ccd2023-11-18T18:18:10ZengMDPI AGAxioms2075-16802023-07-0112769510.3390/axioms12070695Stabilization Control for a Class of Fractional-Order HIV-1 Infection Model with Time DelaysZitong Li0Zhe Zhang1College of Life Sciences, Hunan Normal University, Changsha 410012, ChinaCollege of Electrical and Information Engineering, Hunan University, Changsha 410082, ChinaIn this study, we investigated a novel asymptotic stabilization control method for a fractional-order HIV-1 infection model. First, we constructed a mathematical model of the fractional-order HIV-1 infection using the state-space equations of Caputo fractional calculus. Subsequently, a new control strategy was designed for the fractional-order HIV-1 infection model, and the corresponding asymptotic stabilization criterion was proposed by combining a novel vector Lyapunov function with the M-matrix method. Additionally, we incorporated a time delay, which was generated by the interaction between different variables in the actual system, into the fractional-order HIV-1 infection model, forming a system with a time delay. Based on the vector Lyapunov function associated with the M-matrix measure and Razumikhin interpretation, a control strategy was developed for the fractional-order HIV-1 infection model with a time delay. Finally, we show the results of two numerical simulations of the fractional-order HIV-1 infection model, with and without time delay, to illustrate the accuracy, usefulness, and universality of the proposed measure in our paper.https://www.mdpi.com/2075-1680/12/7/695HIV-1fractional-order infection modelvirus dynamicsstabilization control
spellingShingle Zitong Li
Zhe Zhang
Stabilization Control for a Class of Fractional-Order HIV-1 Infection Model with Time Delays
Axioms
HIV-1
fractional-order infection model
virus dynamics
stabilization control
title Stabilization Control for a Class of Fractional-Order HIV-1 Infection Model with Time Delays
title_full Stabilization Control for a Class of Fractional-Order HIV-1 Infection Model with Time Delays
title_fullStr Stabilization Control for a Class of Fractional-Order HIV-1 Infection Model with Time Delays
title_full_unstemmed Stabilization Control for a Class of Fractional-Order HIV-1 Infection Model with Time Delays
title_short Stabilization Control for a Class of Fractional-Order HIV-1 Infection Model with Time Delays
title_sort stabilization control for a class of fractional order hiv 1 infection model with time delays
topic HIV-1
fractional-order infection model
virus dynamics
stabilization control
url https://www.mdpi.com/2075-1680/12/7/695
work_keys_str_mv AT zitongli stabilizationcontrolforaclassoffractionalorderhiv1infectionmodelwithtimedelays
AT zhezhang stabilizationcontrolforaclassoffractionalorderhiv1infectionmodelwithtimedelays