Risk factors for failure after rotational muscle flap coverage for prosthetic knee infections
Introduction Soft tissue defects are a devastating complication of prosthetic joint infections (PJI) after total knee arthroplasty (TKA). Rotational flaps are commonly utilized to address these defects with variable reports of success. This study aimed to identify predictors of poor outcomes in rota...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2024-01-01
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| Series: | Journal of Orthopaedic Surgery |
| Online Access: | https://doi.org/10.1177/10225536241230349 |
| _version_ | 1827370666184146944 |
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| author | Billy I Kim Colleen M Wixted Andrew M Schwartz William A Jiranek Sean P Ryan Thorsten M Seyler |
| author_facet | Billy I Kim Colleen M Wixted Andrew M Schwartz William A Jiranek Sean P Ryan Thorsten M Seyler |
| author_sort | Billy I Kim |
| collection | DOAJ |
| description | Introduction Soft tissue defects are a devastating complication of prosthetic joint infections (PJI) after total knee arthroplasty (TKA). Rotational flaps are commonly utilized to address these defects with variable reports of success. This study aimed to identify predictors of poor outcomes in rotational muscle flap placement after prosthetic knee infections. The authors hypothesized that outcomes may vary based on infecting pathogen and treatment characteristics. Methods 44 cases of rotational muscle flaps for prosthetic knee infection were retrospectively evaluated at a tertiary referral hospital from 2007 to 2020. Muscle flap types included 39 medial and four lateral gastrocnemius, and one anterior tibialis. Minimum follow-up was 1 year (median: 3.4 years). Primary outcome was flap-related complications. Secondary outcomes included recurrent infection requiring additional surgery, final joint outcomes, and mortality. Results One-year complication-free flap survivorship was 83.9%, recurrent infection-free survivorship was 65.7%, and amputation-free survivorship was 79%. Multivariable cox regression revealed that rheumatoid arthritis diagnosis (HR: 3.4; p = .028) and methicillin-resistant Staphylococcus aureus -positive culture (HR: 4.0; p = .040) had increased risk, while Coagulase-negative Staphylococcus infections had reduced risk for recurrent or persistent infection (HR: 0.2; p = .023). Final joint outcome was retained TKA implant in 18 (40.9%), amputation in 15 (34.1%) patients, and definitive treatment with articulating spacer in 10 (22.7%). 5-years survivorship from death was 71.4%. Conclusion Rotational muscle flaps for soft tissue coverage of the knee are often performed in limb salvage situations with poor survivorship from flap complications, reinfections, and amputation. When considering surgical options for limb salvage, patients should be counseled on these risks. |
| first_indexed | 2024-03-08T10:19:54Z |
| format | Article |
| id | doaj.art-9313fc3ec4004732a0a101b9e7982833 |
| institution | Directory Open Access Journal |
| issn | 2309-4990 |
| language | English |
| last_indexed | 2024-03-08T10:19:54Z |
| publishDate | 2024-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Orthopaedic Surgery |
| spelling | doaj.art-9313fc3ec4004732a0a101b9e79828332024-01-28T03:03:29ZengSAGE PublishingJournal of Orthopaedic Surgery2309-49902024-01-013210.1177/10225536241230349Risk factors for failure after rotational muscle flap coverage for prosthetic knee infectionsBilly I KimColleen M WixtedAndrew M SchwartzWilliam A JiranekSean P RyanThorsten M SeylerIntroduction Soft tissue defects are a devastating complication of prosthetic joint infections (PJI) after total knee arthroplasty (TKA). Rotational flaps are commonly utilized to address these defects with variable reports of success. This study aimed to identify predictors of poor outcomes in rotational muscle flap placement after prosthetic knee infections. The authors hypothesized that outcomes may vary based on infecting pathogen and treatment characteristics. Methods 44 cases of rotational muscle flaps for prosthetic knee infection were retrospectively evaluated at a tertiary referral hospital from 2007 to 2020. Muscle flap types included 39 medial and four lateral gastrocnemius, and one anterior tibialis. Minimum follow-up was 1 year (median: 3.4 years). Primary outcome was flap-related complications. Secondary outcomes included recurrent infection requiring additional surgery, final joint outcomes, and mortality. Results One-year complication-free flap survivorship was 83.9%, recurrent infection-free survivorship was 65.7%, and amputation-free survivorship was 79%. Multivariable cox regression revealed that rheumatoid arthritis diagnosis (HR: 3.4; p = .028) and methicillin-resistant Staphylococcus aureus -positive culture (HR: 4.0; p = .040) had increased risk, while Coagulase-negative Staphylococcus infections had reduced risk for recurrent or persistent infection (HR: 0.2; p = .023). Final joint outcome was retained TKA implant in 18 (40.9%), amputation in 15 (34.1%) patients, and definitive treatment with articulating spacer in 10 (22.7%). 5-years survivorship from death was 71.4%. Conclusion Rotational muscle flaps for soft tissue coverage of the knee are often performed in limb salvage situations with poor survivorship from flap complications, reinfections, and amputation. When considering surgical options for limb salvage, patients should be counseled on these risks.https://doi.org/10.1177/10225536241230349 |
| spellingShingle | Billy I Kim Colleen M Wixted Andrew M Schwartz William A Jiranek Sean P Ryan Thorsten M Seyler Risk factors for failure after rotational muscle flap coverage for prosthetic knee infections Journal of Orthopaedic Surgery |
| title | Risk factors for failure after rotational muscle flap coverage for prosthetic knee infections |
| title_full | Risk factors for failure after rotational muscle flap coverage for prosthetic knee infections |
| title_fullStr | Risk factors for failure after rotational muscle flap coverage for prosthetic knee infections |
| title_full_unstemmed | Risk factors for failure after rotational muscle flap coverage for prosthetic knee infections |
| title_short | Risk factors for failure after rotational muscle flap coverage for prosthetic knee infections |
| title_sort | risk factors for failure after rotational muscle flap coverage for prosthetic knee infections |
| url | https://doi.org/10.1177/10225536241230349 |
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