Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis
Osteoarthritis, which typically arises from aging, traumatic injury, or obesity, is the most common form of arthritis, which usually leads to malfunction of the joints and requires medical interventions due to the poor self-healing capacity of articular cartilage. However, currently used medical tre...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Beilstein-Institut
2022-04-01
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| Series: | Beilstein Journal of Nanotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjnano.13.31 |
| _version_ | 1818468902565314560 |
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| author | Zahra Nabizadeh Mahmoud Nasrollahzadeh Hamed Daemi Mohamadreza Baghaban Eslaminejad Ali Akbar Shabani Mehdi Dadashpour Majid Mirmohammadkhani Davood Nasrabadi |
| author_facet | Zahra Nabizadeh Mahmoud Nasrollahzadeh Hamed Daemi Mohamadreza Baghaban Eslaminejad Ali Akbar Shabani Mehdi Dadashpour Majid Mirmohammadkhani Davood Nasrabadi |
| author_sort | Zahra Nabizadeh |
| collection | DOAJ |
| description | Osteoarthritis, which typically arises from aging, traumatic injury, or obesity, is the most common form of arthritis, which usually leads to malfunction of the joints and requires medical interventions due to the poor self-healing capacity of articular cartilage. However, currently used medical treatment modalities have reported, at least in part, disappointing and frustrating results for patients with osteoarthritis. Recent progress in the design and fabrication of tissue-engineered microscale/nanoscale platforms, which arises from the convergence of stem cell research and nanotechnology methods, has shown promising results in the administration of new and efficient options for treating osteochondral lesions. This paper presents an overview of the recent advances in osteochondral tissue engineering resulting from the application of micro- and nanotechnology approaches in the structure of biomaterials, including biological and microscale/nanoscale topographical cues, microspheres, nanoparticles, nanofibers, and nanotubes. |
| first_indexed | 2024-04-13T21:17:48Z |
| format | Article |
| id | doaj.art-93156f3ae34f427aa81ee8f376acb88b |
| institution | Directory Open Access Journal |
| issn | 2190-4286 |
| language | English |
| last_indexed | 2024-04-13T21:17:48Z |
| publishDate | 2022-04-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Nanotechnology |
| spelling | doaj.art-93156f3ae34f427aa81ee8f376acb88b2022-12-22T02:29:37ZengBeilstein-InstitutBeilstein Journal of Nanotechnology2190-42862022-04-0113136338910.3762/bjnano.13.312190-4286-13-31Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritisZahra Nabizadeh0Mahmoud Nasrollahzadeh1Hamed Daemi2Mohamadreza Baghaban Eslaminejad3Ali Akbar Shabani4Mehdi Dadashpour5Majid Mirmohammadkhani6Davood Nasrabadi7Department of Medical Biotechnology, School of Medicine, Semnan University of Medical Sciences, Semnan, IranDepartment of Chemistry, Faculty of Science, University of Qom, Qom 37185-359, IranDepartment of Cell Engineering, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, IranDepartment of Stem Cell and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, IranDepartment of Medical Biotechnology, School of Medicine, Semnan University of Medical Sciences, Semnan, IranDepartment of Medical Biotechnology, School of Medicine, Semnan University of Medical Sciences, Semnan, IranDepartment of Epidemiology and Biostatistics, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, IranDepartment of Medical Biotechnology, School of Medicine, Semnan University of Medical Sciences, Semnan, IranOsteoarthritis, which typically arises from aging, traumatic injury, or obesity, is the most common form of arthritis, which usually leads to malfunction of the joints and requires medical interventions due to the poor self-healing capacity of articular cartilage. However, currently used medical treatment modalities have reported, at least in part, disappointing and frustrating results for patients with osteoarthritis. Recent progress in the design and fabrication of tissue-engineered microscale/nanoscale platforms, which arises from the convergence of stem cell research and nanotechnology methods, has shown promising results in the administration of new and efficient options for treating osteochondral lesions. This paper presents an overview of the recent advances in osteochondral tissue engineering resulting from the application of micro- and nanotechnology approaches in the structure of biomaterials, including biological and microscale/nanoscale topographical cues, microspheres, nanoparticles, nanofibers, and nanotubes.https://doi.org/10.3762/bjnano.13.31biological cuescartilage regenerationmicro/nanotopographical cuesnanotechnologyosteoarthritisregenerative medicine |
| spellingShingle | Zahra Nabizadeh Mahmoud Nasrollahzadeh Hamed Daemi Mohamadreza Baghaban Eslaminejad Ali Akbar Shabani Mehdi Dadashpour Majid Mirmohammadkhani Davood Nasrabadi Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis Beilstein Journal of Nanotechnology biological cues cartilage regeneration micro/nanotopographical cues nanotechnology osteoarthritis regenerative medicine |
| title | Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis |
| title_full | Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis |
| title_fullStr | Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis |
| title_full_unstemmed | Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis |
| title_short | Micro- and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis |
| title_sort | micro and nanotechnology in biomedical engineering for cartilage tissue regeneration in osteoarthritis |
| topic | biological cues cartilage regeneration micro/nanotopographical cues nanotechnology osteoarthritis regenerative medicine |
| url | https://doi.org/10.3762/bjnano.13.31 |
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