Repeated Irradiation with γ-Ray Induces Cancer Stemness through TGF-β-DLX2 Signaling in the A549 Human Lung Cancer Cell Line

Repeated Irradiation with γ-Ray Induces Cancer Stemness through TGF-β-DLX2 Signaling in the A549 Human Lung Cancer Cell Line

Cancer stem cells (CSCs) play an important role in cancer recurrence and metastasis. It is suggested that the CSC properties in heterogeneous cancer cells can be induced by ionizing radiation (IR). This study investigated the role of DLX2 in the radioresistance and CSC properties induced by IR in NS...

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Bibliographic Details
Main Authors:	Hae-Ran Park, Yeo-Jin Choi, Jee-Young Kim, In-Gyu Kim, Uhee Jung
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Series:	International Journal of Molecular Sciences
Subjects:	ionizing radiation DLX2 non-small cell lung cancer radioresistance cancer stem cell epithelial to mesenchymal transition (EMT)
Online Access:	https://www.mdpi.com/1422-0067/22/8/4284

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