PET-based radiomics visualizes tumor-infiltrating CD8 T cell exhaustion to optimize radiotherapy/immunotherapy combination in mouse models of lung cancer
Abstract Background Cumulative preclinical and clinical evidences showed radiotherapy might augment systemic antitumoral responses to immunotherapy for metastatic non-small cell lung cancer, but the optimal timing of combination is still unclear. The overall infiltration and exhausted subpopulations...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-01-01
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Series: | Biomarker Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40364-023-00454-z |