Right ventricular systolic pressure – Non-invasive bedside predictor of mortality and readmission in heart failure with reduced and preserved ejection fraction hospitalization
Objective: To study the prognostic role of right ventricular systolic pressure (RVSP) in patients with heart failure (HF). Background: Although RVSP is a readily available echocardiographic parameter, it is often underused. Its prognostic role in patients with heart failure is not well established c...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-07-01
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| Series: | Indian Heart Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483222000463 |
| _version_ | 1828358280908374016 |
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| author | Monil Majmundar Tikal Kansara Ashish Kumar Hansang Park Palak Shah Rajkumar Doshi Harshvardhan Zala Hossam Amin Shobhana Chaudhari Ankur Kalra |
| author_facet | Monil Majmundar Tikal Kansara Ashish Kumar Hansang Park Palak Shah Rajkumar Doshi Harshvardhan Zala Hossam Amin Shobhana Chaudhari Ankur Kalra |
| author_sort | Monil Majmundar |
| collection | DOAJ |
| description | Objective: To study the prognostic role of right ventricular systolic pressure (RVSP) in patients with heart failure (HF). Background: Although RVSP is a readily available echocardiographic parameter, it is often underused. Its prognostic role in patients with heart failure is not well established compared with pulmonary artery pressure measured by right heart catheterization. Methods: This single-center retrospective cohort study included patients with acute heart failure hospitalization admitted to the hospital from January 2005 to December 2018. The primary predictor was right ventricular systolic pressure (RVSP) obtained from bedside transthoracic echocardiography at admission. We divided RVSP into two groups, RVSP <40 mm Hg (reference group) and RVSP ≥40 mm Hg. Primary outcome was all-cause mortality. Secondary outcomes were all-cause readmission and cardiac readmission. We conducted propensity-score matching and applied cox-proportional hazard model to compute hazard ratio (HR) with 95% confidence interval (CI). Results: Out of 972 HF patients, 534 patients had RVSP <40 mm Hg and 438 patients had RVSP ≥40 mm Hg. Patients with RVSP ≥40 mm Hg compared with RVSP <40 mm Hg were associated with higher rates of death [HR: 1.60, 95% CI: 1.22–2.09, P-value = 0.001], all-cause readmissions [HR: 1.37, 95% CI: 1.09–1.73, P-value = 0.008] and cardiac readmissions [HR: 1.41, 95% CI: 1.07–1.85, P-value = 0.014]. Conclusion: Higher RVSP (≥40 mm Hg) in HF patients was associated with higher rates of death, all-cause readmissions, and cardiac readmissions. RVSP can be considered as a prognostic marker for mortality and readmission. |
| first_indexed | 2024-04-14T03:27:25Z |
| format | Article |
| id | doaj.art-931a3ce27efb40db888a6e32e0e3f48e |
| institution | Directory Open Access Journal |
| issn | 0019-4832 |
| language | English |
| last_indexed | 2024-04-14T03:27:25Z |
| publishDate | 2022-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj.art-931a3ce27efb40db888a6e32e0e3f48e2022-12-22T02:15:07ZengElsevierIndian Heart Journal0019-48322022-07-01744314321Right ventricular systolic pressure – Non-invasive bedside predictor of mortality and readmission in heart failure with reduced and preserved ejection fraction hospitalizationMonil Majmundar0Tikal Kansara1Ashish Kumar2Hansang Park3Palak Shah4Rajkumar Doshi5Harshvardhan Zala6Hossam Amin7Shobhana Chaudhari8Ankur Kalra9Department of Cardiology, Maimonides Medical Center, Brooklyn, NY, USA; Section of Cardiovascular Research, Heart, Vascular, and Thoracic Department, Cleveland Clinic Akron General, Akron, OH, USADepartment of Internal Medicine, New York Medical College/Metropolitan Hospital, NY, USASection of Cardiovascular Research, Heart, Vascular, and Thoracic Department, Cleveland Clinic Akron General, Akron, OH, USA; Department of Internal Medicine, Cleveland Clinic Akron General, Akron, OH, USADepartment of Internal Medicine, New York Medical College/Metropolitan Hospital, NY, USADepartment of Internal Medicine, New York Medical College/Metropolitan Hospital, NY, USADepartment of Cardiology, St. Joseph's Medical Center, Paterson, NJ, USADepartment of Clinical Research, Icahn School of Medicine, Mount Sinai Hospital, NYC, NY, USADepartment of Internal Medicine, New York Medical College/Metropolitan Hospital, NY, USADepartment of Internal Medicine, New York Medical College/Metropolitan Hospital, NY, USASection of Cardiovascular Research, Heart, Vascular, and Thoracic Department, Cleveland Clinic Akron General, Akron, OH, USA; Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA; Corresponding author. Department of Cardiovascular Medicine Heart, Vascular, and Thoracic Institute, Cleveland Clinic, 225 W Exchange St, Suite 225, Akron, OH, 44302.Objective: To study the prognostic role of right ventricular systolic pressure (RVSP) in patients with heart failure (HF). Background: Although RVSP is a readily available echocardiographic parameter, it is often underused. Its prognostic role in patients with heart failure is not well established compared with pulmonary artery pressure measured by right heart catheterization. Methods: This single-center retrospective cohort study included patients with acute heart failure hospitalization admitted to the hospital from January 2005 to December 2018. The primary predictor was right ventricular systolic pressure (RVSP) obtained from bedside transthoracic echocardiography at admission. We divided RVSP into two groups, RVSP <40 mm Hg (reference group) and RVSP ≥40 mm Hg. Primary outcome was all-cause mortality. Secondary outcomes were all-cause readmission and cardiac readmission. We conducted propensity-score matching and applied cox-proportional hazard model to compute hazard ratio (HR) with 95% confidence interval (CI). Results: Out of 972 HF patients, 534 patients had RVSP <40 mm Hg and 438 patients had RVSP ≥40 mm Hg. Patients with RVSP ≥40 mm Hg compared with RVSP <40 mm Hg were associated with higher rates of death [HR: 1.60, 95% CI: 1.22–2.09, P-value = 0.001], all-cause readmissions [HR: 1.37, 95% CI: 1.09–1.73, P-value = 0.008] and cardiac readmissions [HR: 1.41, 95% CI: 1.07–1.85, P-value = 0.014]. Conclusion: Higher RVSP (≥40 mm Hg) in HF patients was associated with higher rates of death, all-cause readmissions, and cardiac readmissions. RVSP can be considered as a prognostic marker for mortality and readmission.http://www.sciencedirect.com/science/article/pii/S0019483222000463Heart failureRight ventricular systolic pressureDeathReadmission |
| spellingShingle | Monil Majmundar Tikal Kansara Ashish Kumar Hansang Park Palak Shah Rajkumar Doshi Harshvardhan Zala Hossam Amin Shobhana Chaudhari Ankur Kalra Right ventricular systolic pressure – Non-invasive bedside predictor of mortality and readmission in heart failure with reduced and preserved ejection fraction hospitalization Indian Heart Journal Heart failure Right ventricular systolic pressure Death Readmission |
| title | Right ventricular systolic pressure – Non-invasive bedside predictor of mortality and readmission in heart failure with reduced and preserved ejection fraction hospitalization |
| title_full | Right ventricular systolic pressure – Non-invasive bedside predictor of mortality and readmission in heart failure with reduced and preserved ejection fraction hospitalization |
| title_fullStr | Right ventricular systolic pressure – Non-invasive bedside predictor of mortality and readmission in heart failure with reduced and preserved ejection fraction hospitalization |
| title_full_unstemmed | Right ventricular systolic pressure – Non-invasive bedside predictor of mortality and readmission in heart failure with reduced and preserved ejection fraction hospitalization |
| title_short | Right ventricular systolic pressure – Non-invasive bedside predictor of mortality and readmission in heart failure with reduced and preserved ejection fraction hospitalization |
| title_sort | right ventricular systolic pressure non invasive bedside predictor of mortality and readmission in heart failure with reduced and preserved ejection fraction hospitalization |
| topic | Heart failure Right ventricular systolic pressure Death Readmission |
| url | http://www.sciencedirect.com/science/article/pii/S0019483222000463 |
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