COVID-19 and isolation: Risks and implications in the scenario of new variants
With the emergence of new variants of SARS-CoV-2, questions about transmissibility, vaccine efficacy, and impact on mortality are important to support decision-making in public health measures. Modifications related to transmissibility combined with the fact that much of the population has already b...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Brazilian Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1413867022003956 |
| _version_ | 1817986276919345152 |
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| author | Viviane Maria de Carvalho Hessel Dias Alexandre Ferreira Oliveira Ana Karolina Barreto Berselli Marinho Carlos Eduardo dos Santos Ferreira Carlos Eduardo Ferreira Domingues Carlos Magno Castelo Branco Fortaleza Claudia Fernanda de Lacerda Vidal Claudia Maria Dantas de Maio Carrilho Debora Otero Britto Passos Pinheiro Denise Brandão de Assis Eduardo Alexandrino Medeiros Karen Mirna Loro Morejón Leonardo Weissmann Lessandra Michelin Marcelo Carneiro Maria Dolores Santos da Purificação Nogueira Priscila Rosalba Domingos de Oliveira Rafael Junqueira Buralli Raquel Silveira Bello Stucchi Rodrigo Schrage Lins Silvia Figueiredo Costa Alberto Chebabo |
| author_facet | Viviane Maria de Carvalho Hessel Dias Alexandre Ferreira Oliveira Ana Karolina Barreto Berselli Marinho Carlos Eduardo dos Santos Ferreira Carlos Eduardo Ferreira Domingues Carlos Magno Castelo Branco Fortaleza Claudia Fernanda de Lacerda Vidal Claudia Maria Dantas de Maio Carrilho Debora Otero Britto Passos Pinheiro Denise Brandão de Assis Eduardo Alexandrino Medeiros Karen Mirna Loro Morejón Leonardo Weissmann Lessandra Michelin Marcelo Carneiro Maria Dolores Santos da Purificação Nogueira Priscila Rosalba Domingos de Oliveira Rafael Junqueira Buralli Raquel Silveira Bello Stucchi Rodrigo Schrage Lins Silvia Figueiredo Costa Alberto Chebabo |
| author_sort | Viviane Maria de Carvalho Hessel Dias |
| collection | DOAJ |
| description | With the emergence of new variants of SARS-CoV-2, questions about transmissibility, vaccine efficacy, and impact on mortality are important to support decision-making in public health measures. Modifications related to transmissibility combined with the fact that much of the population has already been partially exposed to infection and/or vaccination, have stimulated recommendations to reduce the isolation period for COVID-19. However, these new guidelines have raised questions about their effectiveness in reducing contamination and minimizing impact in work environments. Therefore, a collaborative task force was developed to review the subject in a non-systematic manner, answering questions about SARS-CoV-2 variants, COVID-19 vaccines, isolation/quarantine periods, testing to end the isolation period, and the use of masks as mitigation procedures. Overall, COVID-19 vaccines are effective in preventing severe illness and death but are less effective in preventing infection in the case of the Omicron variant. Any strategy that is adopted to reduce the isolation period should take into consideration the epidemiological situation of the geographical region, individual clinical characteristics, and mask for source control. The use of tests for isolation withdrawal should be evaluated with caution, due to results depending on various conditions and may not be reliable. |
| first_indexed | 2024-04-14T00:06:55Z |
| format | Article |
| id | doaj.art-931ab7768edf4d91afc7bd97dea52529 |
| institution | Directory Open Access Journal |
| issn | 1413-8670 |
| language | English |
| last_indexed | 2024-04-14T00:06:55Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Infectious Diseases |
| spelling | doaj.art-931ab7768edf4d91afc7bd97dea525292022-12-22T02:23:29ZengElsevierBrazilian Journal of Infectious Diseases1413-86702022-09-01265102703COVID-19 and isolation: Risks and implications in the scenario of new variantsViviane Maria de Carvalho Hessel Dias0Alexandre Ferreira Oliveira1Ana Karolina Barreto Berselli Marinho2Carlos Eduardo dos Santos Ferreira3Carlos Eduardo Ferreira Domingues4Carlos Magno Castelo Branco Fortaleza5Claudia Fernanda de Lacerda Vidal6Claudia Maria Dantas de Maio Carrilho7Debora Otero Britto Passos Pinheiro8Denise Brandão de Assis9Eduardo Alexandrino Medeiros10Karen Mirna Loro Morejón11Leonardo Weissmann12Lessandra Michelin13Marcelo Carneiro14Maria Dolores Santos da Purificação Nogueira15Priscila Rosalba Domingos de Oliveira16Rafael Junqueira Buralli17Raquel Silveira Bello Stucchi18Rodrigo Schrage Lins19Silvia Figueiredo Costa20Alberto Chebabo21Associação Brasileira dos Profissionais em Controle de Infecções e Epidemiologia Hospitalar, São Paulo, SP, Brazil; Sociedade Brasileira de Infectologia, São Paulo, SP, Brazil; Hospital Nossa Senhora das Graças, Curitiba, PR, Brazil; Hospital Marcelino Champagnat, Curitiba, PR, Brazil; Corresponding author at: Associação Brasileira dos Profissionais em Controle de Infecções e Epidemiologia Hospitalar-ABIH, Rua Itapeva 486 cj 106 - Bela Vista, São Paulo - SP - Brasil - CEP 01043-000.Sociedade Brasileira de Cirurgia Oncológica, Rio de Janeiro, RJ, BrazilAssociação Brasileira de Alergia e Imunologia, São Paulo, SP, Brazil; Serviço de Imunologia Clínica e Alergia, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, BrazilSociedade Brasileira de Patologia Clínica/Medicina Laboratorial, São Paulo, SP, Brazil; Laboratório Clínico ‒ Hospital Israelita Albert Einstein, São Paulo, SP, Brazil; Laboratório Central ‒ Hospital São Paulo, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, BrazilCoordenação Geral de Segurança e Saúde no Trabalho, Ministério do Trabalho e Previdência, Brasília, DF, BrazilDepartamento de Infectologia, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista (UNESP), Botucatu, SP, BrazilAssociação Brasileira dos Profissionais em Controle de Infecções e Epidemiologia Hospitalar, São Paulo, SP, Brazil; Hospital das Clínicas da Universidade Federal de Pernambuco (HCUFPE), Recife, PE, BrazilHospital Universitário, Universidade Estadual de Londrina, Londrina, PR, BrazilAssociação Brasileira dos Profissionais em Controle de Infecções e Epidemiologia Hospitalar, São Paulo, SP, Brazil; Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ, Brazil; Hospital Universitário Gaffrée e Guinle, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Rio de Janeiro, RJ, BrazilDivisão de Infecção Hospitalar/Centro de Vigilância Epidemiológica Prof. Alexandre Vranjac/Secretaria de Estado da Saúde de São Paulo, São Paulo, SP, BrazilSociedade Brasileira de Infectologia, São Paulo, SP, Brazil; Disciplina de Infectologia, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, BrazilSociedade Brasileira de Infectologia, São Paulo, SP, Brazil; Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, BrazilSociedade Brasileira de Infectologia, São Paulo, SP, Brazil; Instituto de Infectologia Emilio Ribas, São Paulo, SP, Brazil; Faculdade de Medicina, Universidade de Ribeirão Preto (UNAERP), Guarujá, SP, BrazilSociedade Brasileira de Infectologia, São Paulo, SP, Brazil; Programa de Pós-Graduação em Ciências da Saúde, Universidade de Caxias do Sul (UCS), Rio Grande do Sul, RS, BrazilAssociação Brasileira dos Profissionais em Controle de Infecções e Epidemiologia Hospitalar, São Paulo, SP, Brazil; Programa de Pós-Graduação Promoção da Saúde, Universidade de Santa Cruz do Sul (UNISC), Hospital Santa Cruz, Santa Cruz do Sul, RS, BrazilAgência Nacional de Vigilância Sanitária (ANVISA), Brasília, DF, BrazilSociedade Brasileira de Infectologia, São Paulo, SP, Brazil; Instituto de Ortopedia e Traumatologia, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, BrazilCoordenação Geral de Saúde do Trabalhador, Departamento de Saúde Ambiental, do Trabalhador e Vigilância das Emergências em Saúde Pública, Secretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, DF, BrazilSociedade Brasileira de Infectologia, São Paulo, SP, Brazil; Departamento de Clínica Médica, Área de Infectologia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, BrazilSociedade Brasileira de Infectologia, São Paulo, SP, Brazil; Hospital Naval Marcílio Dias, Rio de Janeiro, RJ, BrazilSociedade Brasileira de Infectologia, São Paulo, SP, Brazil; Instituto de Medicina Tropical, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, BrazilSociedade Brasileira de Infectologia, São Paulo, SP, Brazil; Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, BrazilWith the emergence of new variants of SARS-CoV-2, questions about transmissibility, vaccine efficacy, and impact on mortality are important to support decision-making in public health measures. Modifications related to transmissibility combined with the fact that much of the population has already been partially exposed to infection and/or vaccination, have stimulated recommendations to reduce the isolation period for COVID-19. However, these new guidelines have raised questions about their effectiveness in reducing contamination and minimizing impact in work environments. Therefore, a collaborative task force was developed to review the subject in a non-systematic manner, answering questions about SARS-CoV-2 variants, COVID-19 vaccines, isolation/quarantine periods, testing to end the isolation period, and the use of masks as mitigation procedures. Overall, COVID-19 vaccines are effective in preventing severe illness and death but are less effective in preventing infection in the case of the Omicron variant. Any strategy that is adopted to reduce the isolation period should take into consideration the epidemiological situation of the geographical region, individual clinical characteristics, and mask for source control. The use of tests for isolation withdrawal should be evaluated with caution, due to results depending on various conditions and may not be reliable.http://www.sciencedirect.com/science/article/pii/S1413867022003956COVID-19Isolation periodMasksSARS-CoV-2 variantsVaccinesSARS-CoV-2 testing |
| spellingShingle | Viviane Maria de Carvalho Hessel Dias Alexandre Ferreira Oliveira Ana Karolina Barreto Berselli Marinho Carlos Eduardo dos Santos Ferreira Carlos Eduardo Ferreira Domingues Carlos Magno Castelo Branco Fortaleza Claudia Fernanda de Lacerda Vidal Claudia Maria Dantas de Maio Carrilho Debora Otero Britto Passos Pinheiro Denise Brandão de Assis Eduardo Alexandrino Medeiros Karen Mirna Loro Morejón Leonardo Weissmann Lessandra Michelin Marcelo Carneiro Maria Dolores Santos da Purificação Nogueira Priscila Rosalba Domingos de Oliveira Rafael Junqueira Buralli Raquel Silveira Bello Stucchi Rodrigo Schrage Lins Silvia Figueiredo Costa Alberto Chebabo COVID-19 and isolation: Risks and implications in the scenario of new variants Brazilian Journal of Infectious Diseases COVID-19 Isolation period Masks SARS-CoV-2 variants Vaccines SARS-CoV-2 testing |
| title | COVID-19 and isolation: Risks and implications in the scenario of new variants |
| title_full | COVID-19 and isolation: Risks and implications in the scenario of new variants |
| title_fullStr | COVID-19 and isolation: Risks and implications in the scenario of new variants |
| title_full_unstemmed | COVID-19 and isolation: Risks and implications in the scenario of new variants |
| title_short | COVID-19 and isolation: Risks and implications in the scenario of new variants |
| title_sort | covid 19 and isolation risks and implications in the scenario of new variants |
| topic | COVID-19 Isolation period Masks SARS-CoV-2 variants Vaccines SARS-CoV-2 testing |
| url | http://www.sciencedirect.com/science/article/pii/S1413867022003956 |
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