Predicting zeta potential of liposomes from their structure: A nano-QSPR model for DOPE, DC-Chol, DOTAP, and EPC formulations

Predicting zeta potential of liposomes from their structure: A nano-QSPR model for DOPE, DC-Chol, DOTAP, and EPC formulations

Liposomes, nanoscale spherical structures composed of amphiphilic lipids, hold great promise for various pharmaceutical applications, especially as nanocarriers in targeted drug delivery, due to their biocompatibility, biodegradability, and low immunogenicity. Understanding the factors influencing t...

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Bibliographic Details
Main Authors: Kamila Jarzynska, Agnieszka Gajewicz-Skretna, Krzesimir Ciura, Tomasz Puzyn
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Liposomes
Zeta potential
Nano-QSPR
KwLPR
PCA biplot
Nanodescriptors
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037024000126

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