System coagulative and lytic distress-syndrome at the traumatic illness
Purpose - to investigate coagulation-lytic activity of different tissue structures in the early posttraumatic period after pelvic fractures. Material and methods. The study is based on experimental techniques enabling evaluation of hemocoagulation activity of skeletal muscles, liver, kidney, heart,...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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Vreden Russian Research Institute of Traumatology and Orthopedics
2016-09-01
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| Series: | Travmatologiâ i Ortopediâ Rossii |
| Subjects: | |
| Online Access: | https://journal.rniito.org/jour/article/view/47 |
| _version_ | 1819152982074195968 |
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| author | A. P. Vlasov G. A. Shevalayev |
| author_facet | A. P. Vlasov G. A. Shevalayev |
| author_sort | A. P. Vlasov |
| collection | DOAJ |
| description | Purpose - to investigate coagulation-lytic activity of different tissue structures in the early posttraumatic period after pelvic fractures. Material and methods. The study is based on experimental techniques enabling evaluation of hemocoagulation activity of skeletal muscles, liver, kidney, heart, lung, and plasma after pelvic injury (fracture). Results. Changes in coagulation-lytic system after pelvic injury were revealed to evolve not only in blood, but also in different organs (skeletal muscles, liver, kidney, lung, and heart). A systemic coagulation-lytic distress syndrome emerges. General manifestations of hemostasis failure in the early posttraumatic period are characterized by hypercoagulation and inhibition of fibrinolysis. The changes arising are significant in the pathogenesis of thromboembolic complications of traumatic disease. Conclusion. The data obtained in this study suggest a basis for reasonable medical measures aimed at the prevention of critical state of hemocoagulation system by means of target effect on one of its main pathogenetic mechanisms - an extrinsic pathway of blood coagulation. |
| first_indexed | 2024-12-22T14:57:56Z |
| format | Article |
| id | doaj.art-931e7515d4354fe68f2d44395f470d02 |
| institution | Directory Open Access Journal |
| issn | 2311-2905 2542-0933 |
| language | Russian |
| last_indexed | 2024-12-22T14:57:56Z |
| publishDate | 2016-09-01 |
| publisher | Vreden Russian Research Institute of Traumatology and Orthopedics |
| record_format | Article |
| series | Travmatologiâ i Ortopediâ Rossii |
| spelling | doaj.art-931e7515d4354fe68f2d44395f470d022022-12-21T18:22:12ZrusVreden Russian Research Institute of Traumatology and OrthopedicsTravmatologiâ i Ortopediâ Rossii2311-29052542-09332016-09-0101808510.21823/2311-2905-2014-0-1-80-8544System coagulative and lytic distress-syndrome at the traumatic illnessA. P. Vlasov0G. A. Shevalayev1Ogaryov Mordovian State UniversityUlyanovsk State UniversityPurpose - to investigate coagulation-lytic activity of different tissue structures in the early posttraumatic period after pelvic fractures. Material and methods. The study is based on experimental techniques enabling evaluation of hemocoagulation activity of skeletal muscles, liver, kidney, heart, lung, and plasma after pelvic injury (fracture). Results. Changes in coagulation-lytic system after pelvic injury were revealed to evolve not only in blood, but also in different organs (skeletal muscles, liver, kidney, lung, and heart). A systemic coagulation-lytic distress syndrome emerges. General manifestations of hemostasis failure in the early posttraumatic period are characterized by hypercoagulation and inhibition of fibrinolysis. The changes arising are significant in the pathogenesis of thromboembolic complications of traumatic disease. Conclusion. The data obtained in this study suggest a basis for reasonable medical measures aimed at the prevention of critical state of hemocoagulation system by means of target effect on one of its main pathogenetic mechanisms - an extrinsic pathway of blood coagulation.https://journal.rniito.org/jour/article/view/47травма тазасистема гемостазаpelvic traumahemostasis system |
| spellingShingle | A. P. Vlasov G. A. Shevalayev System coagulative and lytic distress-syndrome at the traumatic illness Travmatologiâ i Ortopediâ Rossii травма таза система гемостаза pelvic trauma hemostasis system |
| title | System coagulative and lytic distress-syndrome at the traumatic illness |
| title_full | System coagulative and lytic distress-syndrome at the traumatic illness |
| title_fullStr | System coagulative and lytic distress-syndrome at the traumatic illness |
| title_full_unstemmed | System coagulative and lytic distress-syndrome at the traumatic illness |
| title_short | System coagulative and lytic distress-syndrome at the traumatic illness |
| title_sort | system coagulative and lytic distress syndrome at the traumatic illness |
| topic | травма таза система гемостаза pelvic trauma hemostasis system |
| url | https://journal.rniito.org/jour/article/view/47 |
| work_keys_str_mv | AT apvlasov systemcoagulativeandlyticdistresssyndromeatthetraumaticillness AT gashevalayev systemcoagulativeandlyticdistresssyndromeatthetraumaticillness |