Systemic alterations play a dominant role in epigenetic predisposition to breast cancer in offspring of obese fathers and is transmitted to a second generation

Systemic alterations play a dominant role in epigenetic predisposition to breast cancer in offspring of obese fathers and is transmitted to a second generation

Abstract We previously showed that environmentally-induced epigenetic inheritance of cancer occurs in rodent models. For instance, we reported that paternal consumption of an obesity-inducing diet (OID) increased breast cancer susceptibility in the offspring (F1). Nevertheless, it is still unclear w...

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Bibliographic Details
Main Authors: Camile C. Fontelles, Raquel Santana da Cruz, Alexandra K. Gonsiewski, Ersilia Barin, Volkan Tekmen, Lu Jin, M. Idalia Cruz, Olivier Loudig, Anni Warri, Sonia de Assis
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86548-w

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https://doi.org/10.1038/s41598-021-86548-w

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