Systemic alterations play a dominant role in epigenetic predisposition to breast cancer in offspring of obese fathers and is transmitted to a second generation
Abstract We previously showed that environmentally-induced epigenetic inheritance of cancer occurs in rodent models. For instance, we reported that paternal consumption of an obesity-inducing diet (OID) increased breast cancer susceptibility in the offspring (F1). Nevertheless, it is still unclear w...
Main Authors: | Camile C. Fontelles, Raquel Santana da Cruz, Alexandra K. Gonsiewski, Ersilia Barin, Volkan Tekmen, Lu Jin, M. Idalia Cruz, Olivier Loudig, Anni Warri, Sonia de Assis |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-86548-w |
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