: Type 2 Diabetes and Readmission for Heart Failure

Heart failure is a leading cause for hospitalisation and for readmission, especially in patients over the age of 65. Diabetes is an increasingly common companion to heart failure. The presence of diabetes and its associated comorbidity increases the risk of adverse outcomes and premature mortality i...

Full description

Bibliographic Details
Main Author: Merlin C Thomas
Format: Article
Language:English
Published: SAGE Publishing 2018-06-01
Series:Clinical Medicine Insights: Cardiology
Online Access:https://doi.org/10.1177/1179546818779588
_version_ 1819010584342953984
author Merlin C Thomas
author_facet Merlin C Thomas
author_sort Merlin C Thomas
collection DOAJ
description Heart failure is a leading cause for hospitalisation and for readmission, especially in patients over the age of 65. Diabetes is an increasingly common companion to heart failure. The presence of diabetes and its associated comorbidity increases the risk of adverse outcomes and premature mortality in patients with heart failure. In particular, patients with diabetes are more likely to be readmitted to hospital soon after discharge. This may partly reflect the greater severity of heart disease in these patients. In addition, agents that reduce the chances of readmission such as β-blockers, renin-angiotensin-aldosterone system blockers, and mineralocorticoid receptor antagonists are underutilised because of the perceived increased risks of adverse drug reactions and other limitations. In some cases, readmission to hospital is precipitated by acute decompensation of heart failure (re-exacerbation) leading to pulmonary congestion and/or refractory oedema. However, it appears that for most of the patients admitted and then discharged with a primary diagnosis of heart failure, most readmissions are not due to heart failure, but rather due to comorbidity including arrhythmia, infection, adverse drug reactions, and renal impairment/reduced hydration. All of these are more common in patients who also have diabetes, and all may be partly preventable. The many different reasons for readmission underline the critical value of multidisciplinary comprehensive care in patients admitted with heart failure, especially those with diabetes. A number of new strategies are also being developed to address this area of need, including the use of SGLT2 inhibitors, novel nonsteroidal mineralocorticoid antagonists, and neprilysin inhibitors.
first_indexed 2024-12-21T01:14:35Z
format Article
id doaj.art-93244a844f314bf6965c38280b05c138
institution Directory Open Access Journal
issn 1179-5468
language English
last_indexed 2024-12-21T01:14:35Z
publishDate 2018-06-01
publisher SAGE Publishing
record_format Article
series Clinical Medicine Insights: Cardiology
spelling doaj.art-93244a844f314bf6965c38280b05c1382022-12-21T19:20:49ZengSAGE PublishingClinical Medicine Insights: Cardiology1179-54682018-06-011210.1177/1179546818779588: Type 2 Diabetes and Readmission for Heart FailureMerlin C ThomasHeart failure is a leading cause for hospitalisation and for readmission, especially in patients over the age of 65. Diabetes is an increasingly common companion to heart failure. The presence of diabetes and its associated comorbidity increases the risk of adverse outcomes and premature mortality in patients with heart failure. In particular, patients with diabetes are more likely to be readmitted to hospital soon after discharge. This may partly reflect the greater severity of heart disease in these patients. In addition, agents that reduce the chances of readmission such as β-blockers, renin-angiotensin-aldosterone system blockers, and mineralocorticoid receptor antagonists are underutilised because of the perceived increased risks of adverse drug reactions and other limitations. In some cases, readmission to hospital is precipitated by acute decompensation of heart failure (re-exacerbation) leading to pulmonary congestion and/or refractory oedema. However, it appears that for most of the patients admitted and then discharged with a primary diagnosis of heart failure, most readmissions are not due to heart failure, but rather due to comorbidity including arrhythmia, infection, adverse drug reactions, and renal impairment/reduced hydration. All of these are more common in patients who also have diabetes, and all may be partly preventable. The many different reasons for readmission underline the critical value of multidisciplinary comprehensive care in patients admitted with heart failure, especially those with diabetes. A number of new strategies are also being developed to address this area of need, including the use of SGLT2 inhibitors, novel nonsteroidal mineralocorticoid antagonists, and neprilysin inhibitors.https://doi.org/10.1177/1179546818779588
spellingShingle Merlin C Thomas
: Type 2 Diabetes and Readmission for Heart Failure
Clinical Medicine Insights: Cardiology
title : Type 2 Diabetes and Readmission for Heart Failure
title_full : Type 2 Diabetes and Readmission for Heart Failure
title_fullStr : Type 2 Diabetes and Readmission for Heart Failure
title_full_unstemmed : Type 2 Diabetes and Readmission for Heart Failure
title_short : Type 2 Diabetes and Readmission for Heart Failure
title_sort type 2 diabetes and readmission for heart failure
url https://doi.org/10.1177/1179546818779588
work_keys_str_mv AT merlincthomas type2diabetesandreadmissionforheartfailure