Immunomodulatory effect of macrolides: At what cost?

We present the case of a 60-year old female patient, with a 10 year history of non-CF bronchiectasis and use of macrolides as maintenance immunomodulatory treatment, who was diagnosed with macrolide-resistant Mycobacterium avium complex lung disease. Macrolides' immunomodulatory effect is appea...

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Main Authors: Maria Kipourou, Katerina Manika, Apostolos Papavasileiou, Georgia Pitsiou, Martha Lada, Evangelos Ntinapogias, Ioannis Kioumis
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Respiratory Medicine Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007116300041
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author Maria Kipourou
Katerina Manika
Apostolos Papavasileiou
Georgia Pitsiou
Martha Lada
Evangelos Ntinapogias
Ioannis Kioumis
author_facet Maria Kipourou
Katerina Manika
Apostolos Papavasileiou
Georgia Pitsiou
Martha Lada
Evangelos Ntinapogias
Ioannis Kioumis
author_sort Maria Kipourou
collection DOAJ
description We present the case of a 60-year old female patient, with a 10 year history of non-CF bronchiectasis and use of macrolides as maintenance immunomodulatory treatment, who was diagnosed with macrolide-resistant Mycobacterium avium complex lung disease. Macrolides' immunomodulatory effect is appealing for non- CF bronchiectasis patients, hiding a high risk for resistance emergence.
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spelling doaj.art-93249809e9e04ad89ef684f331f1dfde2022-12-22T00:38:54ZengElsevierRespiratory Medicine Case Reports2213-00712016-01-0117C444610.1016/j.rmcr.2016.01.004Immunomodulatory effect of macrolides: At what cost?Maria Kipourou0Katerina Manika1Apostolos Papavasileiou2Georgia Pitsiou3Martha Lada4Evangelos Ntinapogias5Ioannis Kioumis6Respiratory Infections Unit, Pulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, GreeceRespiratory Infections Unit, Pulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, GreeceTuberculosis Department, 'Sotiria' Chest Diseases Hospital, Athens, GreeceRespiratory Failure Unit, Aristotle University of Thessaloniki, Thessaloniki, GreeceRespiratory Infections Unit, Pulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, GreecePulmonary Department, 424 General Military Hospital, Thessaloniki, GreeceRespiratory Infections Unit, Pulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, GreeceWe present the case of a 60-year old female patient, with a 10 year history of non-CF bronchiectasis and use of macrolides as maintenance immunomodulatory treatment, who was diagnosed with macrolide-resistant Mycobacterium avium complex lung disease. Macrolides' immunomodulatory effect is appealing for non- CF bronchiectasis patients, hiding a high risk for resistance emergence.http://www.sciencedirect.com/science/article/pii/S2213007116300041Non-tuberculous mycobacteriaBronchiectasisMacrolides
spellingShingle Maria Kipourou
Katerina Manika
Apostolos Papavasileiou
Georgia Pitsiou
Martha Lada
Evangelos Ntinapogias
Ioannis Kioumis
Immunomodulatory effect of macrolides: At what cost?
Respiratory Medicine Case Reports
Non-tuberculous mycobacteria
Bronchiectasis
Macrolides
title Immunomodulatory effect of macrolides: At what cost?
title_full Immunomodulatory effect of macrolides: At what cost?
title_fullStr Immunomodulatory effect of macrolides: At what cost?
title_full_unstemmed Immunomodulatory effect of macrolides: At what cost?
title_short Immunomodulatory effect of macrolides: At what cost?
title_sort immunomodulatory effect of macrolides at what cost
topic Non-tuberculous mycobacteria
Bronchiectasis
Macrolides
url http://www.sciencedirect.com/science/article/pii/S2213007116300041
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AT evangelosntinapogias immunomodulatoryeffectofmacrolidesatwhatcost
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