Cocrystals by Design: A Rational Coformer Selection Approach for Tackling the API Problems

Cocrystals by Design: A Rational Coformer Selection Approach for Tackling the API Problems

Active pharmaceutical ingredients (API) with unfavorable physicochemical properties and stability present a significant challenge during their processing into final dosage forms. Cocrystallization of such APIs with suitable coformers is an efficient approach to mitigate the solubility and stability...

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Bibliographic Details
Main Authors: Maan Singh, Harsh Barua, Vaskuri G. S. Sainaga Jyothi, Madhukiran R. Dhondale, Amritha G. Nambiar, Ashish K. Agrawal, Pradeep Kumar, Nalini R. Shastri, Dinesh Kumar
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceutics
Subjects:
coformer
cocrystal
solubility
stability
fumaric acid
oxalic acid
Online Access:https://www.mdpi.com/1999-4923/15/4/1161

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