Folic Acid and Leucovorin Have Potential to Prevent SARS-CoV-2-Virus Internalization by Interacting with S-Glycoprotein/Neuropilin-1 Receptor Complex

Folic Acid and Leucovorin Have Potential to Prevent SARS-CoV-2-Virus Internalization by Interacting with S-Glycoprotein/Neuropilin-1 Receptor Complex

The interaction of the SARS-CoV-2 spike (S) glycoprotein receptor-binding domain with the host-cell ACE2 receptor is a well-known step in virus infection. Neuropilin-1 (NRP-1) is another host factor involved in virus internalization. The interaction between S-glycoprotein and NRP-1 has been identifi...

Full description

Bibliographic Details
Main Authors: Ranko Škrbić, Maja Travar, Miloš P. Stojiljković, Dragan M. Djuric, Relja Suručić
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
COVID-19
folic acid
in silico
in vitro
leucovorin
neuropilin-1
Online Access:https://www.mdpi.com/1420-3049/28/5/2294

Similar Items

Similar Items