Efficacy of preladenant in improving motor symptoms in Parkinson's disease: A systematic review and meta-analysis

Efficacy of preladenant in improving motor symptoms in Parkinson's disease: A systematic review and meta-analysis

Background: Parkinson's disease (PD) is a complex neurodegenerative disorder characterized by dopamine depletion and severe motor impairments. Preladenant, an adenosine A2 receptor antagonist, is an investigational treatment for PD. This systematic review and meta-analysis aimed to critically e...

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Bibliographic Details
Main Authors: Mohammad Amin Karimi, Alireza Ghajari, Reza Khademi, Mohammad Hossein Etemadi, Narges Safar Firouz, Behnaz Mohammadvand, Kimia Janeshin, Afra Darvishi, Shafagh Asgarzadeh, Sayedeh-Fatemeh Sadat-Madani, Mohammad Abbasalizadeh, Zahra Jafari Shendi, Ata Akhtari Kohnehshahri, Niloofar Deravi, Seyed Amirhossein Mazhari, Mahsa Aziz, Matin Bidares, Mohaddeseh Belbasi, Mahdyieh Naziri, Hossein Ashkpour Motlagh
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:IBRO Neuroscience Reports
Subjects:
Preladenant
Parkinson's disease
Adenosine A2 receptor antagonist
Motor symptoms
Motor fluctuations
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242124000666

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http://www.sciencedirect.com/science/article/pii/S2667242124000666

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