Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes

Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes

Mesenchymal stem cell (MSC) exosomes have been found to attenuate cardiac systolic and diastolic dysfunction in animal models of ischemia. Exosomes carry a plethora of active and inactive proteins as their cargo, which are readily available to the recipient cell for use in intracellular signaling pa...

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Bibliographic Details
Main Authors: Rajshekhar A. Kore, Samir V. Jenkins, Azemat Jamshidi-Parsian, Alan J. Tackett, Robert J. Griffin, Srinivas Ayyadevara, Jawahar L. Mehta
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Mesenchymal stem cell exosomes
Myocardial ischemia
Post-ischemic fibrosis
Proteomics
Transcription factors
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823000444

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http://www.sciencedirect.com/science/article/pii/S2405580823000444

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