Thoroughly Calibrated Modular Agent-Based Model of the Human Cardiovascular and Renal Systems for Blood Pressure Regulation in Health and Disease
Here we present a modular agent-based mathematical model of the human cardiovascular and renal systems. It integrates the previous models primarily developed by A. C. Guyton, F. Karaaslan, K. M. Hallow, and Y. V. Solodyannikov. We performed the model calibration to find an equilibrium state within t...
Main Authors: | Elena Kutumova, Ilya Kiselev, Ruslan Sharipov, Galina Lifshits, Fedor Kolpakov |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-11-01
|
Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2021.746300/full |
Similar Items
-
Mathematical modeling of antihypertensive therapy
by: Elena Kutumova, et al.
Published: (2022-12-01) -
Modular Representation of Physiologically Based Pharmacokinetic Models: Nanoparticle Delivery to Solid Tumors in Mice as an Example
by: Elena Kutumova, et al.
Published: (2022-04-01) -
Mathematical modelling of the influence of ACE I/D polymorphism on blood pressure and antihypertensive therapy
by: Elena Kutumova, et al.
Published: (2024-05-01) -
Computational master-regulator search reveals mTOR and PI3K pathways responsible for low sensitivity of NCI-H292 and A427 lung cancer cell lines to cytotoxic action of p53 activator Nutlin-3
by: Ulyana Boyarskikh, et al.
Published: (2018-02-01) -
Assessment of transcriptional importance of cell line-specific features based on GTRD and FANTOM5 data.
by: Ruslan N Sharipov, et al.
Published: (2020-01-01)