Exploration and stabilization of Ras1 mating zone: A mechanism with positive and negative feedbacks.

Exploration and stabilization of Ras1 mating zone: A mechanism with positive and negative feedbacks.

In mating fission yeast cells, sensing and response to extracellular pheromone concentrations occurs through an exploratory Cdc42 patch that stochastically samples the cell cortex before stabilizing towards a mating partner. Active Ras1 (Ras1-GTP), an upstream regulator of Cdc42, and Gap1, the GTPas...

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Bibliographic Details
Main Authors: Bita Khalili, Laura Merlini, Vincent Vincenzetti, Sophie G Martin, Dimitrios Vavylonis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1006317&type=printable

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