Pharmacokinetics of esomeprazole in goats (Capra aegagrus hircus) after intravenous and subcutaneous administration

Pharmacokinetics of esomeprazole in goats (Capra aegagrus hircus) after intravenous and subcutaneous administration

BackgroundStressed and hospitalized goats are at risk of developing abomasal (gastric) ulceration, but there is a paucity of pharmacokinetic studies for proton pump inhibiting drugs, such as, esomeprazole in goats.ObjectivesThe objectives for this study were to estimate plasma pharmacokinetic parame...

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Bibliographic Details
Main Authors: Rachel Fladung, Joe S. Smith, Melissa T. Hines, Windy Michelle Soto-Gonzalez, Bryanna Fayne, Rebecca R. Rahn, Olivia Grace Escher, Lainey Harvill, Joan Bergman, Jessica D. Garcia, Amanda Jo Kreuder, Sherry Cox
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Veterinary Science
Subjects:
proton pump inhibitor
ulcer
goat (Capra aegagrus hircus)
pharmacokinetics
esomeprazole
ruminant
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2022.968973/full

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