Gingival plasma cell granuloma
Plasma cell granuloma is a rare reactive lesion composed of polyclonal plasma cells. It manifests primarily in the lungs, but may occur in various other anatomic locations like the oral cavity. Intraoral plasma cell granulomas involving the tongue, lip, oral mucosa and gingiva have been reported in...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2010-01-01
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| Series: | Indian Journal of Dental Research |
| Subjects: | |
| Online Access: | http://www.ijdr.in/article.asp?issn=0970-9290;year=2010;volume=21;issue=3;spage=460;epage=462;aulast=Phadnaik |
| _version_ | 1818297612183273472 |
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| author | Phadnaik Mangesh Attar Nilofar |
| author_facet | Phadnaik Mangesh Attar Nilofar |
| author_sort | Phadnaik Mangesh |
| collection | DOAJ |
| description | Plasma cell granuloma is a rare reactive lesion composed of polyclonal plasma cells. It manifests primarily in the lungs, but may occur in various other anatomic locations like the oral cavity. Intraoral plasma cell granulomas involving the tongue, lip, oral mucosa and gingiva have been reported in the past. This case presents a 54-year-old female with chronic periodontitis and mandibular anterior gingival overgrowth treated by Phase I therapy (scaling and root planing) and excisional biopsy. Histological examination revealed inflammatory cell infiltrate containing sheets of plasma cells. Immunohistochemistry for kappa and lambda light chains showed a polyclonal staining pattern confirming a diagnosis of plasma cell granuloma. This case highlights the need to biopsy for unusual lesions to rule out potential neoplasms. |
| first_indexed | 2024-12-13T04:22:12Z |
| format | Article |
| id | doaj.art-93381cb12f34453f995d376e6f9babeb |
| institution | Directory Open Access Journal |
| issn | 0970-9290 1998-3603 |
| language | English |
| last_indexed | 2024-12-13T04:22:12Z |
| publishDate | 2010-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dental Research |
| spelling | doaj.art-93381cb12f34453f995d376e6f9babeb2022-12-21T23:59:45ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032010-01-01213460462Gingival plasma cell granulomaPhadnaik MangeshAttar NilofarPlasma cell granuloma is a rare reactive lesion composed of polyclonal plasma cells. It manifests primarily in the lungs, but may occur in various other anatomic locations like the oral cavity. Intraoral plasma cell granulomas involving the tongue, lip, oral mucosa and gingiva have been reported in the past. This case presents a 54-year-old female with chronic periodontitis and mandibular anterior gingival overgrowth treated by Phase I therapy (scaling and root planing) and excisional biopsy. Histological examination revealed inflammatory cell infiltrate containing sheets of plasma cells. Immunohistochemistry for kappa and lambda light chains showed a polyclonal staining pattern confirming a diagnosis of plasma cell granuloma. This case highlights the need to biopsy for unusual lesions to rule out potential neoplasms.http://www.ijdr.in/article.asp?issn=0970-9290;year=2010;volume=21;issue=3;spage=460;epage=462;aulast=PhadnaikChronic periodontitisimmunohistochemistrypolyclonal plasma cell granulomareactive lesion |
| spellingShingle | Phadnaik Mangesh Attar Nilofar Gingival plasma cell granuloma Indian Journal of Dental Research Chronic periodontitis immunohistochemistry polyclonal plasma cell granuloma reactive lesion |
| title | Gingival plasma cell granuloma |
| title_full | Gingival plasma cell granuloma |
| title_fullStr | Gingival plasma cell granuloma |
| title_full_unstemmed | Gingival plasma cell granuloma |
| title_short | Gingival plasma cell granuloma |
| title_sort | gingival plasma cell granuloma |
| topic | Chronic periodontitis immunohistochemistry polyclonal plasma cell granuloma reactive lesion |
| url | http://www.ijdr.in/article.asp?issn=0970-9290;year=2010;volume=21;issue=3;spage=460;epage=462;aulast=Phadnaik |
| work_keys_str_mv | AT phadnaikmangesh gingivalplasmacellgranuloma AT attarnilofar gingivalplasmacellgranuloma |