Insulin Resistance in young obese females with and without Polycystic Ovary Syndrome.

Background: The present study intends to determine the comparative insulin resistance (IR) among young obese females with and without polycystic ovary syndrome (PCOs) using the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR). Methodology: During this comparative cross-sectional stud...

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Main Authors: Maheen Shehzad, Naila Abdul Sattar, Nadia Ishaq
Format: Article
Language:English
Published: Advance Educational Institute & Research Centre 2022-01-01
Series:International Journal of Endorsing Health Science Research
Subjects:
Online Access:http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/798
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author Maheen Shehzad
Naila Abdul Sattar
Nadia Ishaq
author_facet Maheen Shehzad
Naila Abdul Sattar
Nadia Ishaq
author_sort Maheen Shehzad
collection DOAJ
description Background: The present study intends to determine the comparative insulin resistance (IR) among young obese females with and without polycystic ovary syndrome (PCOs) using the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR). Methodology: During this comparative cross-sectional study, a total of 300 young obese females were evaluated for the presence of PCOS and insulin resistance. Based on the PCOs diagnosis, 250 obese PCOs females were included in group 1, and group 2 comprised 50 obese non-PCOs females. With the demographic details, patients' diabetic and lipid profiles were also evaluated, and the difference in the inference between the groups was drawn using SPSS version 22.0. Results: It is to note that more than 90% of the young obese PCOs females were diagnosed with type 2 diabetes mellitus (T2DM) while none of the obese non-PCOs females had diabetes. Furthermore, the HOMA-IR score was significantly high among young obese females diagnosed with PCOs (16.30 ± 1.62) as compared to those without PCOs (3.47 ± 0.37) (p<0.01). Conclusion: It is concluded from the study results that young obese females with PCOS are more prone to develop insulin resistance than those without PCOs.
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spelling doaj.art-9339527ca4534fe48c9ad5e7c665869e2022-12-21T23:51:21ZengAdvance Educational Institute & Research CentreInternational Journal of Endorsing Health Science Research2307-37482310-38412022-01-0194Insulin Resistance in young obese females with and without Polycystic Ovary Syndrome.Maheen Shehzad0Naila Abdul Sattar1Nadia Ishaq2Alraheem medical complex, GM Abad, Faisalabad-PakistanGovernment College Women University, Faisalabad-PakistanGovernment College Women University, Faisalabad-Pakistan Background: The present study intends to determine the comparative insulin resistance (IR) among young obese females with and without polycystic ovary syndrome (PCOs) using the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR). Methodology: During this comparative cross-sectional study, a total of 300 young obese females were evaluated for the presence of PCOS and insulin resistance. Based on the PCOs diagnosis, 250 obese PCOs females were included in group 1, and group 2 comprised 50 obese non-PCOs females. With the demographic details, patients' diabetic and lipid profiles were also evaluated, and the difference in the inference between the groups was drawn using SPSS version 22.0. Results: It is to note that more than 90% of the young obese PCOs females were diagnosed with type 2 diabetes mellitus (T2DM) while none of the obese non-PCOs females had diabetes. Furthermore, the HOMA-IR score was significantly high among young obese females diagnosed with PCOs (16.30 ± 1.62) as compared to those without PCOs (3.47 ± 0.37) (p<0.01). Conclusion: It is concluded from the study results that young obese females with PCOS are more prone to develop insulin resistance than those without PCOs. http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/798Obesity, Polycystic Ovary Syndrome, Insulin Resistance, HOMA-IR
spellingShingle Maheen Shehzad
Naila Abdul Sattar
Nadia Ishaq
Insulin Resistance in young obese females with and without Polycystic Ovary Syndrome.
International Journal of Endorsing Health Science Research
Obesity, Polycystic Ovary Syndrome, Insulin Resistance, HOMA-IR
title Insulin Resistance in young obese females with and without Polycystic Ovary Syndrome.
title_full Insulin Resistance in young obese females with and without Polycystic Ovary Syndrome.
title_fullStr Insulin Resistance in young obese females with and without Polycystic Ovary Syndrome.
title_full_unstemmed Insulin Resistance in young obese females with and without Polycystic Ovary Syndrome.
title_short Insulin Resistance in young obese females with and without Polycystic Ovary Syndrome.
title_sort insulin resistance in young obese females with and without polycystic ovary syndrome
topic Obesity, Polycystic Ovary Syndrome, Insulin Resistance, HOMA-IR
url http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/798
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