Leveraging Immunopeptidomics To Study and Combat Infectious Disease
T cells must recognize pathogen-derived peptides bound to major histocompatibility complexes (MHCs) in order to initiate a cell-mediated immune response against an infection, or to support the development of high-affinity antibody responses. Identifying antigens presented on MHCs by infected cells a...
| المؤلفون الرئيسيون: | , , |
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| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
American Society for Microbiology
2021-08-01
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| سلاسل: | mSystems |
| الوصول للمادة أونلاين: | https://journals.asm.org/doi/10.1128/mSystems.00310-21 |
| الملخص: | T cells must recognize pathogen-derived peptides bound to major histocompatibility complexes (MHCs) in order to initiate a cell-mediated immune response against an infection, or to support the development of high-affinity antibody responses. Identifying antigens presented on MHCs by infected cells and professional antigen-presenting cells (APCs) during infection may therefore provide a route toward developing new vaccines. |
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| تدمد: | 2379-5077 |