Leveraging Immunopeptidomics To Study and Combat Infectious Disease
T cells must recognize pathogen-derived peptides bound to major histocompatibility complexes (MHCs) in order to initiate a cell-mediated immune response against an infection, or to support the development of high-affinity antibody responses. Identifying antigens presented on MHCs by infected cells a...
| Hlavní autoři: | , , |
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| Médium: | Článek |
| Jazyk: | English |
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American Society for Microbiology
2021-08-01
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| Edice: | mSystems |
| On-line přístup: | https://journals.asm.org/doi/10.1128/mSystems.00310-21 |
| Shrnutí: | T cells must recognize pathogen-derived peptides bound to major histocompatibility complexes (MHCs) in order to initiate a cell-mediated immune response against an infection, or to support the development of high-affinity antibody responses. Identifying antigens presented on MHCs by infected cells and professional antigen-presenting cells (APCs) during infection may therefore provide a route toward developing new vaccines. |
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| ISSN: | 2379-5077 |