Phenotypic Selection of Dairy Cattle Infected with Bovine Leukemia Virus Demonstrates Immunogenetic Resilience through NGS-Based Genotyping of BoLA MHC Class II Genes

Phenotypic Selection of Dairy Cattle Infected with Bovine Leukemia Virus Demonstrates Immunogenetic Resilience through NGS-Based Genotyping of BoLA MHC Class II Genes

Characterization of the bovine leukocyte antigen (BoLA) DRB3 gene has shown that specific alleles associate with susceptibility or resilience to the progression of bovine leukemia virus (BLV), measured by proviral load (PVL). Through surveillance of multi-farm BLV eradication field trials, we observ...

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Bibliographic Details
Main Authors: Chaelynne E. Lohr, Kelly R. B. Sporer, Kelsey A. Brigham, Laura A. Pavliscak, Matelyn M. Mason, Andrew Borgman, Vickie J. Ruggiero, Tasia M. Taxis, Paul C. Bartlett, Casey J. Droscha
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pathogens
Subjects:
bovine leukemia virus
ELISA
proviral load
BoLA
MHC Class II
sequence-based typing
Online Access:https://www.mdpi.com/2076-0817/11/1/104

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