Coronary Computed Tomography Angiography and Abdominal Aortic Calcification Screening among High-Risk Living Kidney Donors
Background: A unique scanning protocol combining coronary computed tomography angiography (CTA) with routine abdominal CTA is being used at the Rabin Medical Center as a method of screening high-risk candidates for living kidney donation. We aim to evaluate the potential impact of coronary CTA on th...
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| Format: | Article |
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MDPI AG
2023-07-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/13/4541 |
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| author | Keren Skalsky Arthur Shiyovich Nir Hochwald Amos Levi Lutof Zreik Shlomit Tamir Gideon Shafir Anat Briger Ruth Rahamimov Ran Kornowski Ashraf Hamdan |
| author_facet | Keren Skalsky Arthur Shiyovich Nir Hochwald Amos Levi Lutof Zreik Shlomit Tamir Gideon Shafir Anat Briger Ruth Rahamimov Ran Kornowski Ashraf Hamdan |
| author_sort | Keren Skalsky |
| collection | DOAJ |
| description | Background: A unique scanning protocol combining coronary computed tomography angiography (CTA) with routine abdominal CTA is being used at the Rabin Medical Center as a method of screening high-risk candidates for living kidney donation. We aim to evaluate the potential impact of coronary CTA on the decision regarding eligibility for kidney donation and its correlation with abdominal aortic calcification (AAC). Methods: CCTA and abdominal CTA results of potential living kidney donors evaluated for donation between September 2020 and November 2021 were retrieved. A retrospective analysis of the abdominal CTA was used to calculate the AAC. Patients’ demographic, clinical, and imaging data were collected from the electronic files, as well as the final decision regarding eligibility for donation. Results: A total of 62 potential kidney donors were evaluated for donation using the combined scan. The mean age was 53.8 years, with male predominance (59.7%). Significant coronary artery stenosis (≥70% luminal stenosis) was present in two patients (3.2%), whereas five patients (8%) had moderate stenosis (50–69%). Thirteen patients (21%) were disqualified from donation due to moderate-to-significant coronary artery disease or abdominal atherosclerosis. The correlation between the coronary artery calcium score and the AAC was found to be positive, with a Pearson correlation coefficient of 0.88 (<i>p</i> < 0.001). Conclusions: The use of coronary CTA in the evaluation of potential kidney donors may has a potential impact on the decision regarding eligibility for donation. A high correlation between the coronary artery calcium score and the AAC was found. |
| first_indexed | 2024-03-11T01:37:17Z |
| format | Article |
| id | doaj.art-934810a3616a431f9fb5c31d503aa235 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T01:37:17Z |
| publishDate | 2023-07-01 |
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| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-934810a3616a431f9fb5c31d503aa2352023-11-18T16:55:22ZengMDPI AGJournal of Clinical Medicine2077-03832023-07-011213454110.3390/jcm12134541Coronary Computed Tomography Angiography and Abdominal Aortic Calcification Screening among High-Risk Living Kidney DonorsKeren Skalsky0Arthur Shiyovich1Nir Hochwald2Amos Levi3Lutof Zreik4Shlomit Tamir5Gideon Shafir6Anat Briger7Ruth Rahamimov8Ran Kornowski9Ashraf Hamdan10Department of Cardiology, Rabin Medical Center, Petach-Tikva 4941492, IsraelDepartment of Cardiology, Rabin Medical Center, Petach-Tikva 4941492, IsraelDepartment of Cardiology, Rabin Medical Center, Petach-Tikva 4941492, IsraelDepartment of Cardiology, Rabin Medical Center, Petach-Tikva 4941492, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelFaculty of Medicine, Tel Aviv University, Tel Aviv 6997801, IsraelDepartment of Cardiology, Rabin Medical Center, Petach-Tikva 4941492, IsraelDepartment of Cardiology, Rabin Medical Center, Petach-Tikva 4941492, IsraelBackground: A unique scanning protocol combining coronary computed tomography angiography (CTA) with routine abdominal CTA is being used at the Rabin Medical Center as a method of screening high-risk candidates for living kidney donation. We aim to evaluate the potential impact of coronary CTA on the decision regarding eligibility for kidney donation and its correlation with abdominal aortic calcification (AAC). Methods: CCTA and abdominal CTA results of potential living kidney donors evaluated for donation between September 2020 and November 2021 were retrieved. A retrospective analysis of the abdominal CTA was used to calculate the AAC. Patients’ demographic, clinical, and imaging data were collected from the electronic files, as well as the final decision regarding eligibility for donation. Results: A total of 62 potential kidney donors were evaluated for donation using the combined scan. The mean age was 53.8 years, with male predominance (59.7%). Significant coronary artery stenosis (≥70% luminal stenosis) was present in two patients (3.2%), whereas five patients (8%) had moderate stenosis (50–69%). Thirteen patients (21%) were disqualified from donation due to moderate-to-significant coronary artery disease or abdominal atherosclerosis. The correlation between the coronary artery calcium score and the AAC was found to be positive, with a Pearson correlation coefficient of 0.88 (<i>p</i> < 0.001). Conclusions: The use of coronary CTA in the evaluation of potential kidney donors may has a potential impact on the decision regarding eligibility for donation. A high correlation between the coronary artery calcium score and the AAC was found.https://www.mdpi.com/2077-0383/12/13/4541living kidney donorscardiovascular riskcoronary CTA |
| spellingShingle | Keren Skalsky Arthur Shiyovich Nir Hochwald Amos Levi Lutof Zreik Shlomit Tamir Gideon Shafir Anat Briger Ruth Rahamimov Ran Kornowski Ashraf Hamdan Coronary Computed Tomography Angiography and Abdominal Aortic Calcification Screening among High-Risk Living Kidney Donors Journal of Clinical Medicine living kidney donors cardiovascular risk coronary CTA |
| title | Coronary Computed Tomography Angiography and Abdominal Aortic Calcification Screening among High-Risk Living Kidney Donors |
| title_full | Coronary Computed Tomography Angiography and Abdominal Aortic Calcification Screening among High-Risk Living Kidney Donors |
| title_fullStr | Coronary Computed Tomography Angiography and Abdominal Aortic Calcification Screening among High-Risk Living Kidney Donors |
| title_full_unstemmed | Coronary Computed Tomography Angiography and Abdominal Aortic Calcification Screening among High-Risk Living Kidney Donors |
| title_short | Coronary Computed Tomography Angiography and Abdominal Aortic Calcification Screening among High-Risk Living Kidney Donors |
| title_sort | coronary computed tomography angiography and abdominal aortic calcification screening among high risk living kidney donors |
| topic | living kidney donors cardiovascular risk coronary CTA |
| url | https://www.mdpi.com/2077-0383/12/13/4541 |
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