Effect of Ulinastatin on Syndecan-2-Mediated Vascular Damage in IDH2-Deficient Endothelial Cells
Syndecan-2 (SDC2), a cell-surface heparin sulfate proteoglycan of the glycocalyx, is mainly expressed in endothelial cells. Although oxidative stress and inflammatory mediators have been shown to mediate dysfunction of the glycocalyx, little is known about their role in vascular endothelial cells. I...
Main Authors: | Su-jeong Choi, Harsha Nagar, Jun Wan Lee, Seonhee Kim, Ikjun Lee, Shuyu Piao, Byeong Hwa Jeon, Cuk-Seong Kim |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-01-01
|
Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/10/1/187 |
Similar Items
-
IDH2 Deficiency Promotes Endothelial Senescence by Eliciting miR-34b/c-Mediated Suppression of Mitophagy and Increased ROS Production
by: Ikjun Lee, et al.
Published: (2023-02-01) -
The effect of ulinastatin on hemostasis in major orthopedic surgery
by: Jin Young Lee, et al.
Published: (2010-01-01) -
Oncogenetic landscape and clinical impact of IDH1 and IDH2 mutations in T-ALL
by: Mathieu Simonin, et al.
Published: (2021-05-01) -
Evaluation of the Pharmacological Function of Ulinastatin in Experimental Animals
by: Ling Guo, et al.
Published: (2012-07-01) -
Effect of ulinastatin on perioperative organ function and systemic inflammatory reaction during cardiac surgery: a randomized double-blinded study
by: Jieun Song, et al.
Published: (2013-04-01)