GAF is essential for zygotic genome activation and chromatin accessibility in the early Drosophila embryo

GAF is essential for zygotic genome activation and chromatin accessibility in the early Drosophila embryo

Following fertilization, the genomes of the germ cells are reprogrammed to form the totipotent embryo. Pioneer transcription factors are essential for remodeling the chromatin and driving the initial wave of zygotic gene expression. In Drosophila melanogaster, the pioneer factor Zelda is essential f...

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Bibliographic Details
Main Authors: Marissa M Gaskill, Tyler J Gibson, Elizabeth D Larson, Melissa M Harrison
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-03-01
Series:eLife
Subjects:
transcription
zygotic genome activation
maternal-to-zygotic transition
pioneer factor
chromatin
Online Access:https://elifesciences.org/articles/66668

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