p20BAP31 induces cell apoptosis via both AIF caspase-independent and the ROS/JNK mitochondrial pathway in colorectal cancer
Abstract Background During cell apoptosis, the C-terminus of BAP31 is cleaved by caspase-8 and generates p20BAP31, which has been shown to induce an apoptotic pathway between the endoplasmic reticulum (ER) and mitochondria. However, the underlying mechanisms of p20BAP31 in cell apoptosis remains unc...
Main Authors: | Xiaohan Jiang, Guoxun Li, Benzhi Zhu, Jingnan Zang, Tian Lan, Rui Jiang, Bing Wang |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-03-01
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Series: | Cellular & Molecular Biology Letters |
Subjects: | |
Online Access: | https://doi.org/10.1186/s11658-023-00434-z |
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