Effects of prenatal exposure to combined stress on memory retention of passive avoidance learning in rats
Background: Many studies have shown that prenatal stress affects development of fetal brain. Objective: The aim of this study was to evaluate the effect of prenatal exposure to combined stress on memory retention of passive avoidance learning in rats. Methods: This experimental study was performed...
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| Format: | Article |
| Language: | fas |
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Qazvin University of Medical Sciences & Health Services
2015-10-01
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| Series: | The Journal of Qazvin University of Medical Sciences |
| Subjects: | |
| Online Access: | http://journal.qums.ac.ir/browse.php?a_id=1974&slc_lang=en&sid=1&ftxt=1 |
| _version_ | 1831728578529591296 |
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| author | Z. Homauni Afshari M. Sofiabadi M. Dezfulian H. Haghdost Yazdy |
| author_facet | Z. Homauni Afshari M. Sofiabadi M. Dezfulian H. Haghdost Yazdy |
| author_sort | Z. Homauni Afshari |
| collection | DOAJ |
| description | Background: Many studies have shown that prenatal stress affects development of fetal brain.
Objective: The aim of this study was to evaluate the effect of prenatal exposure to combined stress on memory retention of passive avoidance learning in rats.
Methods: This experimental study was performed on 16 male and 16 female Wistar rats in 2014. The rats were divided into four groups: male and female control groups, with natural pregnancy and two male and female treatment groups with exposure to combined stress (electromagnetic field, immobility and social stress) in the second and third weeks of embryonic development. The learning was evaluated using shuttle box setup. Data were analyzed using ANOVA and Tukey test.
Findings: The prenatal combined stress caused decrease in the latency time to enter the dark chamber in male and female new born rats in post-training periods especially the second week compared to the control groups.
Conclusion: With regards to the results, prenatal exposure to combined stress can reduce the memory retention of passive avoidance learning. |
| first_indexed | 2024-12-21T06:52:49Z |
| format | Article |
| id | doaj.art-93532ebc83d348ab8a7bb20a54ec6187 |
| institution | Directory Open Access Journal |
| issn | 1561-3666 2228-7213 |
| language | fas |
| last_indexed | 2024-12-21T06:52:49Z |
| publishDate | 2015-10-01 |
| publisher | Qazvin University of Medical Sciences & Health Services |
| record_format | Article |
| series | The Journal of Qazvin University of Medical Sciences |
| spelling | doaj.art-93532ebc83d348ab8a7bb20a54ec61872022-12-21T19:12:26ZfasQazvin University of Medical Sciences & Health ServicesThe Journal of Qazvin University of Medical Sciences1561-36662228-72132015-10-011941218Effects of prenatal exposure to combined stress on memory retention of passive avoidance learning in ratsZ. Homauni AfshariM. SofiabadiM. DezfulianH. Haghdost YazdyBackground: Many studies have shown that prenatal stress affects development of fetal brain. Objective: The aim of this study was to evaluate the effect of prenatal exposure to combined stress on memory retention of passive avoidance learning in rats. Methods: This experimental study was performed on 16 male and 16 female Wistar rats in 2014. The rats were divided into four groups: male and female control groups, with natural pregnancy and two male and female treatment groups with exposure to combined stress (electromagnetic field, immobility and social stress) in the second and third weeks of embryonic development. The learning was evaluated using shuttle box setup. Data were analyzed using ANOVA and Tukey test. Findings: The prenatal combined stress caused decrease in the latency time to enter the dark chamber in male and female new born rats in post-training periods especially the second week compared to the control groups. Conclusion: With regards to the results, prenatal exposure to combined stress can reduce the memory retention of passive avoidance learning.http://journal.qums.ac.ir/browse.php?a_id=1974&slc_lang=en&sid=1&ftxt=1LearningPregnancyMemoryRats |
| spellingShingle | Z. Homauni Afshari M. Sofiabadi M. Dezfulian H. Haghdost Yazdy Effects of prenatal exposure to combined stress on memory retention of passive avoidance learning in rats The Journal of Qazvin University of Medical Sciences Learning Pregnancy Memory Rats |
| title | Effects of prenatal exposure to combined stress on memory retention of passive avoidance learning in rats |
| title_full | Effects of prenatal exposure to combined stress on memory retention of passive avoidance learning in rats |
| title_fullStr | Effects of prenatal exposure to combined stress on memory retention of passive avoidance learning in rats |
| title_full_unstemmed | Effects of prenatal exposure to combined stress on memory retention of passive avoidance learning in rats |
| title_short | Effects of prenatal exposure to combined stress on memory retention of passive avoidance learning in rats |
| title_sort | effects of prenatal exposure to combined stress on memory retention of passive avoidance learning in rats |
| topic | Learning Pregnancy Memory Rats |
| url | http://journal.qums.ac.ir/browse.php?a_id=1974&slc_lang=en&sid=1&ftxt=1 |
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