Modulation of Membrane Microviscosity by Protein-Mediated Carotenoid Delivery as Revealed by Time-Resolved Fluorescence Anisotropy

Modulation of Membrane Microviscosity by Protein-Mediated Carotenoid Delivery as Revealed by Time-Resolved Fluorescence Anisotropy

Carotenoids are potent antioxidants with a wide range of biomedical applications. However, their delivery into human cells is challenging and relatively inefficient. While the use of natural water-soluble carotenoproteins capable to reversibly bind carotenoids and transfer them into membranes is pro...

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Bibliographic Details
Main Authors: Alexey N. Semenov, Danil A. Gvozdev, Dmitry V. Zlenko, Elena A. Protasova, Anastasia R. Khashimova, Evgenia Yu. Parshina, Adil A. Baizhumanov, Natalia Yu. Lotosh, Eleonora E. Kim, Yuriy N. Kononevich, Alexey A. Pakhomov, Alla A. Selishcheva, Nikolai N. Sluchanko, Evgeny A. Shirshin, Eugene G. Maksimov
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Membranes
Subjects:
carotenoproteins
carotenoid delivery
membrane microviscosity
time-resolved fluorescence anisotropy
FRET
molecular dynamics
Online Access:https://www.mdpi.com/2077-0375/12/10/905

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