The Emerging Link Between the Complement Cascade and Purinergic Signaling in Stress Hematopoiesis

The Emerging Link Between the Complement Cascade and Purinergic Signaling in Stress Hematopoiesis

Innate immunity plays an important role in orchestrating the immune response, and the complement cascade (ComC) is a major component of this ancient defense system, which is activated by the classical-, alternative-, or mannan-binding lectin (MBL) pathways. However, the MBL-dependent ComC-activation...

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Bibliographic Details
Main Authors: Mariusz Z. Ratajczak, Mateusz Adamiak, Magda Kucia, William Tse, Janina Ratajczak, Wieslaw Wiktor-Jedrzejczak
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
complement cascade
ATP
mannan-binding lectin
sterile inflammation
purinergic signaling
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01295/full

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