Landscape of sialylation patterns identify biomarkers for diagnosis and prediction of response to anti-TNF therapy in crohn’s disease

Landscape of sialylation patterns identify biomarkers for diagnosis and prediction of response to anti-TNF therapy in crohn’s disease

Crohn’s disease (CD), a subtype of inflammatory bowel disease (IBD), causes chronic gastrointestinal tract inflammation. Thirty percent of patients do not respond to anti-tumor necrosis factor (TNF) therapy. Sialylation is involved in the pathogenesis of IBD. We aimed to identify potential biomarker...

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Bibliographic Details
Main Authors: Chenglin Ye, Sizhe Zhu, Yuan Gao, Yabing Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Genetics
Subjects:
crohn’s disease
anti-TNF therapy
sialylation
immune infiltration
bioinformatics analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1065297/full

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