Psychiatric uses of topiramate: What is the current evidence?
Topiramate enhances gamma-amino-butyric acid effects, has anti- glutaminergic effects, and is a state-dependent sodium channel blocker. 1 It is registered as an adjunctive treatment for epilepsy but is not registered for psychiatric indications. Nevertheless, it may be useful beyond its initial indi...
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| Format: | Article |
| Language: | English |
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AOSIS
2008-06-01
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| Series: | South African Journal of Psychiatry |
| Online Access: | http://www.sajp.org.za/index.php/sajp/article/view/157 |
| _version_ | 1811234177448673280 |
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| author | Pierre M Joubert |
| author_facet | Pierre M Joubert |
| author_sort | Pierre M Joubert |
| collection | DOAJ |
| description | Topiramate enhances gamma-amino-butyric acid effects, has anti- glutaminergic effects, and is a state-dependent sodium channel blocker. 1 It is registered as an adjunctive treatment for epilepsy but is not registered for psychiatric indications. Nevertheless, it may be useful beyond its initial indication, considering the promising literature on which I report below. However, much more research evidence is needed to establish sufficient scientific justification for prescribing it routinely for psychiatric purposes. |
| first_indexed | 2024-04-12T11:32:19Z |
| format | Article |
| id | doaj.art-9361ca78b3e2449cb645b7ea01c0132f |
| institution | Directory Open Access Journal |
| issn | 1608-9685 2078-6786 |
| language | English |
| last_indexed | 2024-04-12T11:32:19Z |
| publishDate | 2008-06-01 |
| publisher | AOSIS |
| record_format | Article |
| series | South African Journal of Psychiatry |
| spelling | doaj.art-9361ca78b3e2449cb645b7ea01c0132f2022-12-22T03:34:58ZengAOSISSouth African Journal of Psychiatry1608-96852078-67862008-06-0114210.4102/sajpsychiatry.v14i2.157169Psychiatric uses of topiramate: What is the current evidence?Pierre M Joubert0Department of Psychiatry, School of Medicine, Faculty of Health Sciences, University of Pretoria and Weskoppies Hospital, PretoriaTopiramate enhances gamma-amino-butyric acid effects, has anti- glutaminergic effects, and is a state-dependent sodium channel blocker. 1 It is registered as an adjunctive treatment for epilepsy but is not registered for psychiatric indications. Nevertheless, it may be useful beyond its initial indication, considering the promising literature on which I report below. However, much more research evidence is needed to establish sufficient scientific justification for prescribing it routinely for psychiatric purposes.http://www.sajp.org.za/index.php/sajp/article/view/157 |
| spellingShingle | Pierre M Joubert Psychiatric uses of topiramate: What is the current evidence? South African Journal of Psychiatry |
| title | Psychiatric uses of topiramate: What is the current evidence? |
| title_full | Psychiatric uses of topiramate: What is the current evidence? |
| title_fullStr | Psychiatric uses of topiramate: What is the current evidence? |
| title_full_unstemmed | Psychiatric uses of topiramate: What is the current evidence? |
| title_short | Psychiatric uses of topiramate: What is the current evidence? |
| title_sort | psychiatric uses of topiramate what is the current evidence |
| url | http://www.sajp.org.za/index.php/sajp/article/view/157 |
| work_keys_str_mv | AT pierremjoubert psychiatricusesoftopiramatewhatisthecurrentevidence |