Evaluation of the antibacterial effect of titanium dioxide nanoparticles combined with acrylic laminates for functional orthodontic appliances: a randomized controlled clinical trial
Abstract Background The objective of this study was to evaluate the antibacterial effect of titanium dioxide nanoparticles incorporated into the acrylic baseplates of the maxillary part of twin block appliances in orthodontic patients during the treatment period. Materials and methods Twenty-six pat...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | BMC Oral Health |
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| Online Access: | https://doi.org/10.1186/s12903-023-03805-2 |
| _version_ | 1797362858760077312 |
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| author | Ghada M. Elabd Waleed Eldars Marwa S. Shamaa Marwa A. Tawfik |
| author_facet | Ghada M. Elabd Waleed Eldars Marwa S. Shamaa Marwa A. Tawfik |
| author_sort | Ghada M. Elabd |
| collection | DOAJ |
| description | Abstract Background The objective of this study was to evaluate the antibacterial effect of titanium dioxide nanoparticles incorporated into the acrylic baseplates of the maxillary part of twin block appliances in orthodontic patients during the treatment period. Materials and methods Twenty-six patients were selected randomly and divided into two groups(n = 13). Test group patients used orthodontic functional appliances containing 1% titanium dioxide nanoparticles in acrylic baseplates. Control group patients used orthodontic functional appliances without titanium dioxide nanoparticles in acrylic baseplates. Swap samples were taken from the palatal gingiva facing the fitting surface of the acrylic component of the maxillary part of a twin block appliance for each patient at five-time intervals (baseline sample, after one, two, four, and six months) and then cultured in blood agar plates to calculate bacterial colony count. The Mann‒Whitney U test and the Friedman test were used to compare data. Bonferroni correction (p value ≤ 0.05) was applied to detect significant differences. The results showed a decrease in the bacterial colony count in the test group compared to the control group. Pairwise comparisons revealed a statistically significant difference in samples after four- and six-month groups (p values = 0.002 and 0.011, respectively) vs. the one-month test group. A higher statistically significant difference was observed in the six-month group (p-value = 0.037) vs. the baseline group in the control group. Conclusion The addition of 1% titanium dioxide nanoparticles to acrylic baseplates of orthodontic functional appliances significantly reduced the bacterial colony count under the base plate after at least four months of application. |
| first_indexed | 2024-03-08T16:12:29Z |
| format | Article |
| id | doaj.art-9365bb18e4e6412aaaf315cd54aae8c6 |
| institution | Directory Open Access Journal |
| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-03-08T16:12:29Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-9365bb18e4e6412aaaf315cd54aae8c62024-01-07T12:51:23ZengBMCBMC Oral Health1472-68312024-01-0124111010.1186/s12903-023-03805-2Evaluation of the antibacterial effect of titanium dioxide nanoparticles combined with acrylic laminates for functional orthodontic appliances: a randomized controlled clinical trialGhada M. Elabd0Waleed Eldars1Marwa S. Shamaa2Marwa A. Tawfik3Department of Orthodontics, Faculty of Dentistry, Mansoura UniversityDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Mansoura UniversityDepartment of Orthodontics, Faculty of Dentistry, Mansoura UniversityDepartment of Orthodontics, Faculty of Dentistry, Mansoura UniversityAbstract Background The objective of this study was to evaluate the antibacterial effect of titanium dioxide nanoparticles incorporated into the acrylic baseplates of the maxillary part of twin block appliances in orthodontic patients during the treatment period. Materials and methods Twenty-six patients were selected randomly and divided into two groups(n = 13). Test group patients used orthodontic functional appliances containing 1% titanium dioxide nanoparticles in acrylic baseplates. Control group patients used orthodontic functional appliances without titanium dioxide nanoparticles in acrylic baseplates. Swap samples were taken from the palatal gingiva facing the fitting surface of the acrylic component of the maxillary part of a twin block appliance for each patient at five-time intervals (baseline sample, after one, two, four, and six months) and then cultured in blood agar plates to calculate bacterial colony count. The Mann‒Whitney U test and the Friedman test were used to compare data. Bonferroni correction (p value ≤ 0.05) was applied to detect significant differences. The results showed a decrease in the bacterial colony count in the test group compared to the control group. Pairwise comparisons revealed a statistically significant difference in samples after four- and six-month groups (p values = 0.002 and 0.011, respectively) vs. the one-month test group. A higher statistically significant difference was observed in the six-month group (p-value = 0.037) vs. the baseline group in the control group. Conclusion The addition of 1% titanium dioxide nanoparticles to acrylic baseplates of orthodontic functional appliances significantly reduced the bacterial colony count under the base plate after at least four months of application.https://doi.org/10.1186/s12903-023-03805-2Antibacterial activityOrthodontic functional appliancesTitanium dioxide nanoparticles |
| spellingShingle | Ghada M. Elabd Waleed Eldars Marwa S. Shamaa Marwa A. Tawfik Evaluation of the antibacterial effect of titanium dioxide nanoparticles combined with acrylic laminates for functional orthodontic appliances: a randomized controlled clinical trial BMC Oral Health Antibacterial activity Orthodontic functional appliances Titanium dioxide nanoparticles |
| title | Evaluation of the antibacterial effect of titanium dioxide nanoparticles combined with acrylic laminates for functional orthodontic appliances: a randomized controlled clinical trial |
| title_full | Evaluation of the antibacterial effect of titanium dioxide nanoparticles combined with acrylic laminates for functional orthodontic appliances: a randomized controlled clinical trial |
| title_fullStr | Evaluation of the antibacterial effect of titanium dioxide nanoparticles combined with acrylic laminates for functional orthodontic appliances: a randomized controlled clinical trial |
| title_full_unstemmed | Evaluation of the antibacterial effect of titanium dioxide nanoparticles combined with acrylic laminates for functional orthodontic appliances: a randomized controlled clinical trial |
| title_short | Evaluation of the antibacterial effect of titanium dioxide nanoparticles combined with acrylic laminates for functional orthodontic appliances: a randomized controlled clinical trial |
| title_sort | evaluation of the antibacterial effect of titanium dioxide nanoparticles combined with acrylic laminates for functional orthodontic appliances a randomized controlled clinical trial |
| topic | Antibacterial activity Orthodontic functional appliances Titanium dioxide nanoparticles |
| url | https://doi.org/10.1186/s12903-023-03805-2 |
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