Metabolic engineering for the microbial production of isoprenoids: Carotenoids and isoprenoid-based biofuels

Isoprenoids are the most abundant and highly diverse group of natural products. Many isoprenoids have been used for pharmaceuticals, nutraceuticals, flavors, cosmetics, food additives and biofuels. Carotenoids and isoprenoid-based biofuels are two classes of important isoprenoids. These isoprenoids...

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Main Authors: Fu-Xing Niu, Qian Lu, Yi-Fan Bu, Jian-Zhong Liu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2017-09-01
Series:Synthetic and Systems Biotechnology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X17300157
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author Fu-Xing Niu
Qian Lu
Yi-Fan Bu
Jian-Zhong Liu
author_facet Fu-Xing Niu
Qian Lu
Yi-Fan Bu
Jian-Zhong Liu
author_sort Fu-Xing Niu
collection DOAJ
description Isoprenoids are the most abundant and highly diverse group of natural products. Many isoprenoids have been used for pharmaceuticals, nutraceuticals, flavors, cosmetics, food additives and biofuels. Carotenoids and isoprenoid-based biofuels are two classes of important isoprenoids. These isoprenoids have been produced microbially through metabolic engineering and synthetic biology efforts. Herein, we briefly review the engineered biosynthetic pathways in well-characterized microbial systems for the production of carotenoids and several isoprenoid-based biofuels.
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spelling doaj.art-9369821e8f5342229118ab6647a65db92024-04-16T21:24:57ZengKeAi Communications Co., Ltd.Synthetic and Systems Biotechnology2405-805X2017-09-012316717510.1016/j.synbio.2017.08.001Metabolic engineering for the microbial production of isoprenoids: Carotenoids and isoprenoid-based biofuelsFu-Xing Niu0Qian Lu1Yi-Fan Bu2Jian-Zhong Liu3Biotechnology Research Center and Biomedical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, ChinaBiotechnology Research Center and Biomedical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, ChinaBiotechnology Research Center and Biomedical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, ChinaBiotechnology Research Center and Biomedical Center, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, ChinaIsoprenoids are the most abundant and highly diverse group of natural products. Many isoprenoids have been used for pharmaceuticals, nutraceuticals, flavors, cosmetics, food additives and biofuels. Carotenoids and isoprenoid-based biofuels are two classes of important isoprenoids. These isoprenoids have been produced microbially through metabolic engineering and synthetic biology efforts. Herein, we briefly review the engineered biosynthetic pathways in well-characterized microbial systems for the production of carotenoids and several isoprenoid-based biofuels.http://www.sciencedirect.com/science/article/pii/S2405805X17300157CarotenoidsIsoprenoid-based biofuelMetabolic engineeringSynthetic biology
spellingShingle Fu-Xing Niu
Qian Lu
Yi-Fan Bu
Jian-Zhong Liu
Metabolic engineering for the microbial production of isoprenoids: Carotenoids and isoprenoid-based biofuels
Synthetic and Systems Biotechnology
Carotenoids
Isoprenoid-based biofuel
Metabolic engineering
Synthetic biology
title Metabolic engineering for the microbial production of isoprenoids: Carotenoids and isoprenoid-based biofuels
title_full Metabolic engineering for the microbial production of isoprenoids: Carotenoids and isoprenoid-based biofuels
title_fullStr Metabolic engineering for the microbial production of isoprenoids: Carotenoids and isoprenoid-based biofuels
title_full_unstemmed Metabolic engineering for the microbial production of isoprenoids: Carotenoids and isoprenoid-based biofuels
title_short Metabolic engineering for the microbial production of isoprenoids: Carotenoids and isoprenoid-based biofuels
title_sort metabolic engineering for the microbial production of isoprenoids carotenoids and isoprenoid based biofuels
topic Carotenoids
Isoprenoid-based biofuel
Metabolic engineering
Synthetic biology
url http://www.sciencedirect.com/science/article/pii/S2405805X17300157
work_keys_str_mv AT fuxingniu metabolicengineeringforthemicrobialproductionofisoprenoidscarotenoidsandisoprenoidbasedbiofuels
AT qianlu metabolicengineeringforthemicrobialproductionofisoprenoidscarotenoidsandisoprenoidbasedbiofuels
AT yifanbu metabolicengineeringforthemicrobialproductionofisoprenoidscarotenoidsandisoprenoidbasedbiofuels
AT jianzhongliu metabolicengineeringforthemicrobialproductionofisoprenoidscarotenoidsandisoprenoidbasedbiofuels