Resolvin D1 Reduces Lung Infection and Inflammation Activating Resolution in Cystic Fibrosis

Resolvin D1 Reduces Lung Infection and Inflammation Activating Resolution in Cystic Fibrosis

Non-resolving lung inflammation and Pseudomonas aeruginosa infections are the underlying cause of morbidity and mortality in cystic fibrosis (CF). The endogenous lipid mediator resolvin (Rv) D1 is a potent regulator of resolution, and its roles, actions, and therapeutic potential in CF are of intere...

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Bibliographic Details
Main Authors: Elisa Isopi, Domenico Mattoscio, Marilina Codagnone, Veronica Cecilia Mari, Alessia Lamolinara, Sara Patruno, Marco D’Aurora, Eleonora Cianci, Annalisa Nespoli, Sara Franchi, Valentina Gatta, Marc Dubourdeau, Paolo Moretti, Maria Di Sabatino, Manuela Iezzi, Mario Romano, Antonio Recchiuti
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
pro-resolving lipid mediators (SPM)
inflammation
resolution
macrophages
neutrophils
infection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00581/full

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