Whole Transcriptome Analysis Reveals That Filifactor alocis Modulates TNFα-Stimulated MAPK Activation in Human Neutrophils

Whole Transcriptome Analysis Reveals That Filifactor alocis Modulates TNFα-Stimulated MAPK Activation in Human Neutrophils

Periodontitis is an irreversible, bacteria-induced, chronic inflammatory disease that compromises the integrity of tooth-supporting tissues and adversely affects systemic health. As the immune system's first line of defense against bacteria, neutrophils use their microbicidal functions in the o...

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Bibliographic Details
Main Authors: Irina Miralda, Aruna Vashishta, Max N. Rogers, Eric C. Rouchka, Xiaohong Li, Sabine Waigel, Richard J. Lamont, Silvia M. Uriarte
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
human neutrophils
periodontitis
emerging oral pathogens
MAPK signaling
neutrophil transcriptome
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00497/full

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