The Efficacy and Safety of Radiofrequency Ablation for Bilateral Papillary Thyroid Microcarcinoma
ObjectiveTo investigate the long-term clinical results of radiofrequency ablation (RFA) for bilateral papillary thyroid microcarcinoma (PTMC).Materials and MethodsFrom October 2014 to February 2018, 47 patients (37 females, 10 males, mean age 43.39 ± 9.26 years) with 100 bilateral PTMC (mean volume...
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| Format: | Article |
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Frontiers Media S.A.
2021-06-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2021.663636/full |
| _version_ | 1818836723555106816 |
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| author | Lin Yan Mingbo Zhang Qing Song Jing Xiao Ying Zhang Yukun Luo |
| author_facet | Lin Yan Mingbo Zhang Qing Song Jing Xiao Ying Zhang Yukun Luo |
| author_sort | Lin Yan |
| collection | DOAJ |
| description | ObjectiveTo investigate the long-term clinical results of radiofrequency ablation (RFA) for bilateral papillary thyroid microcarcinoma (PTMC).Materials and MethodsFrom October 2014 to February 2018, 47 patients (37 females, 10 males, mean age 43.39 ± 9.26 years) with 100 bilateral PTMC (mean volume 75.22 ± 73.87 mm3) treated by RFA were included in this retrospective study. Bilateral PTMC was defined as at least one tumor located in the contralateral lobe. Patients were followed up at 1, 3, 6, 12 months and every 6–12 months thereafter. Volume, volume reduction ratio (VRR) and local tumor recurrence were evaluated during the follow-up period.ResultsAfter a mean follow-up period of 47.77 ± 11.54 months, the mean volume of bilateral PTMC decreased from 75.22 ± 73.87 mm3 to 0.09 ± 0.44 mm3. The mean VRR was 99.94 ± 0.28% and the complete disappearance rate was 92.00%. During the follow-up, one patient (2.13%) developed lymph node metastasis and two patients (4.26%) had recurrent PTMC. All the recurrent lesions underwent additional RFA and two of them disappeared completely. No life-threatening or delayed complications occurred.ConclusionsWith sufficient preoperative evaluation, RFA might be a promising alternative for bilateral PTMC patients who were unsuitable for surgery or refused surgery. |
| first_indexed | 2024-12-19T03:11:08Z |
| format | Article |
| id | doaj.art-936c14bc829c40ffaec5d4505641c604 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-12-19T03:11:08Z |
| publishDate | 2021-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-936c14bc829c40ffaec5d4505641c6042022-12-21T20:38:01ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922021-06-011210.3389/fendo.2021.663636663636The Efficacy and Safety of Radiofrequency Ablation for Bilateral Papillary Thyroid MicrocarcinomaLin YanMingbo ZhangQing SongJing XiaoYing ZhangYukun LuoObjectiveTo investigate the long-term clinical results of radiofrequency ablation (RFA) for bilateral papillary thyroid microcarcinoma (PTMC).Materials and MethodsFrom October 2014 to February 2018, 47 patients (37 females, 10 males, mean age 43.39 ± 9.26 years) with 100 bilateral PTMC (mean volume 75.22 ± 73.87 mm3) treated by RFA were included in this retrospective study. Bilateral PTMC was defined as at least one tumor located in the contralateral lobe. Patients were followed up at 1, 3, 6, 12 months and every 6–12 months thereafter. Volume, volume reduction ratio (VRR) and local tumor recurrence were evaluated during the follow-up period.ResultsAfter a mean follow-up period of 47.77 ± 11.54 months, the mean volume of bilateral PTMC decreased from 75.22 ± 73.87 mm3 to 0.09 ± 0.44 mm3. The mean VRR was 99.94 ± 0.28% and the complete disappearance rate was 92.00%. During the follow-up, one patient (2.13%) developed lymph node metastasis and two patients (4.26%) had recurrent PTMC. All the recurrent lesions underwent additional RFA and two of them disappeared completely. No life-threatening or delayed complications occurred.ConclusionsWith sufficient preoperative evaluation, RFA might be a promising alternative for bilateral PTMC patients who were unsuitable for surgery or refused surgery.https://www.frontiersin.org/articles/10.3389/fendo.2021.663636/fullradiofrequency ablationpapillary thyroid carcinomathyroidultrasoundclinical outcomes |
| spellingShingle | Lin Yan Mingbo Zhang Qing Song Jing Xiao Ying Zhang Yukun Luo The Efficacy and Safety of Radiofrequency Ablation for Bilateral Papillary Thyroid Microcarcinoma Frontiers in Endocrinology radiofrequency ablation papillary thyroid carcinoma thyroid ultrasound clinical outcomes |
| title | The Efficacy and Safety of Radiofrequency Ablation for Bilateral Papillary Thyroid Microcarcinoma |
| title_full | The Efficacy and Safety of Radiofrequency Ablation for Bilateral Papillary Thyroid Microcarcinoma |
| title_fullStr | The Efficacy and Safety of Radiofrequency Ablation for Bilateral Papillary Thyroid Microcarcinoma |
| title_full_unstemmed | The Efficacy and Safety of Radiofrequency Ablation for Bilateral Papillary Thyroid Microcarcinoma |
| title_short | The Efficacy and Safety of Radiofrequency Ablation for Bilateral Papillary Thyroid Microcarcinoma |
| title_sort | efficacy and safety of radiofrequency ablation for bilateral papillary thyroid microcarcinoma |
| topic | radiofrequency ablation papillary thyroid carcinoma thyroid ultrasound clinical outcomes |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2021.663636/full |
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