COE Inhibits Vasculogenic Mimicry by Targeting EphA2 in Hepatocellular Carcinoma, a Research Based on Proteomics Analysis

COE Inhibits Vasculogenic Mimicry by Targeting EphA2 in Hepatocellular Carcinoma, a Research Based on Proteomics Analysis

New strategies and drugs are urgently needed to improve the treatment of hepatocellular carcinoma (HCC). Vasculogenic mimicry (VM) has been elucidated being associated with the progression of HCC and anti-VM could be a promising strategy. Celastrus orbiculatus extract (COE), a mixture of 26 compound...

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Bibliographic Details
Main Authors: Zewen Chu, Xin Shi, Gaoyang Chen, Xuejun He, Yayun Qian, Haibo Wang, Li Tao, Yanqing Liu, Wei Jiang, Jue Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
vasculogenesis mimicry
hepatocel lular carcinoma
EphA2
protemics
cancer treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.619732/full

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