Relative Bioavailability of Orally Dispersible Tablet Formulations of Levo‐ and Racemic Praziquantel: Two Phase I Studies

Relative Bioavailability of Orally Dispersible Tablet Formulations of Levo‐ and Racemic Praziquantel: Two Phase I Studies

Orally dispersible tablet (ODT) formulations of levo praziquantel (L‐PZQ) and racemic PZQ (rac‐PZQ) are being developed to treat schistosomiasis in preschool‐aged children. Two crossover studies (N = 32 and 36, respectively) assessed the relative bioavailability of these ODTs vs. Cysticide in adults...

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Bibliographic Details
Main Authors: Wilhelmina Maria Bagchus, Deon Bezuidenhout, Eleanor Harrison‐Moench, Elly Kourany‐Lefoll, Peter Wolna, Oezkan Yalkinoglu
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.12601

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