The role of inflammatory mediators in renal vascular remodeling in patients with arterial hypertension
The relationship between level of pro-inflammatory cytokines and processes of remodeling of intra-renal vessels in patients with essential arterial hypertension (EAH) were studied. Were surveyed 80 patients with EAH. Ambulatory blood pressure monitoring and renal artery doppler ultrasound were perfo...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2014-10-01
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| Series: | Кубанский научный медицинский вестник |
| Subjects: | |
| Online Access: | https://ksma.elpub.ru/jour/article/view/209 |
| _version_ | 1797295618824077312 |
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| author | E. S. Krutikov S. I. Chistyakova |
| author_facet | E. S. Krutikov S. I. Chistyakova |
| author_sort | E. S. Krutikov |
| collection | DOAJ |
| description | The relationship between level of pro-inflammatory cytokines and processes of remodeling of intra-renal vessels in patients with essential arterial hypertension (EAH) were studied. Were surveyed 80 patients with EAH. Ambulatory blood pressure monitoring and renal artery doppler ultrasound were performed all patients. Further we determined the level of IL-1, IL-6, TNF-α. It was found that patients with EAH and overweight, there are more significant changes in circadian blood pressure profile and renal hemodynamics. Significant correlation between IL-6, TNF-α and indicators of the remodeling intra-renal vessels were identified. It may indicate that processes of nonspecific inflammation causes the structural alteration of the renal vascular in the patients with EAH. |
| first_indexed | 2024-03-07T21:50:31Z |
| format | Article |
| id | doaj.art-936d047ec46a4be48bf7f03b506a7259 |
| institution | Directory Open Access Journal |
| issn | 1608-6228 2541-9544 |
| language | Russian |
| last_indexed | 2024-03-07T21:50:31Z |
| publishDate | 2014-10-01 |
| publisher | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” |
| record_format | Article |
| series | Кубанский научный медицинский вестник |
| spelling | doaj.art-936d047ec46a4be48bf7f03b506a72592024-02-25T10:57:15ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442014-10-015667110.25207/1608-6228-2014-5-66-71209The role of inflammatory mediators in renal vascular remodeling in patients with arterial hypertensionE. S. Krutikov0S. I. Chistyakova1ГУ «Крымский государственный медицинский университет имени С.И. Георгиевского»; КРУ «КТМО «Университетская клиника»ГУ «Крымский государственный медицинский университет имени С.И. Георгиевского»; КРУ «КТМО «Университетская клиника»The relationship between level of pro-inflammatory cytokines and processes of remodeling of intra-renal vessels in patients with essential arterial hypertension (EAH) were studied. Were surveyed 80 patients with EAH. Ambulatory blood pressure monitoring and renal artery doppler ultrasound were performed all patients. Further we determined the level of IL-1, IL-6, TNF-α. It was found that patients with EAH and overweight, there are more significant changes in circadian blood pressure profile and renal hemodynamics. Significant correlation between IL-6, TNF-α and indicators of the remodeling intra-renal vessels were identified. It may indicate that processes of nonspecific inflammation causes the structural alteration of the renal vascular in the patients with EAH.https://ksma.elpub.ru/jour/article/view/209эссенциальная артериальная гипертензияизбыточная масса телапровоспалительные цитокиныремоделирование сосудов почекarterial hypertensionoverweightpro-inflammatory cytokinesremodeling of intra-renal vessels |
| spellingShingle | E. S. Krutikov S. I. Chistyakova The role of inflammatory mediators in renal vascular remodeling in patients with arterial hypertension Кубанский научный медицинский вестник эссенциальная артериальная гипертензия избыточная масса тела провоспалительные цитокины ремоделирование сосудов почек arterial hypertension overweight pro-inflammatory cytokines remodeling of intra-renal vessels |
| title | The role of inflammatory mediators in renal vascular remodeling in patients with arterial hypertension |
| title_full | The role of inflammatory mediators in renal vascular remodeling in patients with arterial hypertension |
| title_fullStr | The role of inflammatory mediators in renal vascular remodeling in patients with arterial hypertension |
| title_full_unstemmed | The role of inflammatory mediators in renal vascular remodeling in patients with arterial hypertension |
| title_short | The role of inflammatory mediators in renal vascular remodeling in patients with arterial hypertension |
| title_sort | role of inflammatory mediators in renal vascular remodeling in patients with arterial hypertension |
| topic | эссенциальная артериальная гипертензия избыточная масса тела провоспалительные цитокины ремоделирование сосудов почек arterial hypertension overweight pro-inflammatory cytokines remodeling of intra-renal vessels |
| url | https://ksma.elpub.ru/jour/article/view/209 |
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