Prevalence of symptoms in patients poisoned with iron in Ahvaz Razi Hospital in 2014-2017

Background: Iron is an important element for normal cell metabolism, but in excess amounts is quite cytotoxic, and even deadly. Iron poisoning is a calamity repeated many times in the world. The clinical signs of the patients include gastrointestinal symptoms, a short period of relative stability, C...

Full description

Bibliographic Details
Main Authors: Ali hassan Rahmani, Shahrzad Molavinia, Fatemeh Boustani
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2020-09-01
Series:Asia Pacific Journal of Medical Toxicology
Subjects:
Online Access:https://apjmt.mums.ac.ir/article_16751_349d6de1217faadd1eab6a3e10158765.pdf
_version_ 1818107465842032640
author Ali hassan Rahmani
Shahrzad Molavinia
Fatemeh Boustani
author_facet Ali hassan Rahmani
Shahrzad Molavinia
Fatemeh Boustani
author_sort Ali hassan Rahmani
collection DOAJ
description Background: Iron is an important element for normal cell metabolism, but in excess amounts is quite cytotoxic, and even deadly. Iron poisoning is a calamity repeated many times in the world. The clinical signs of the patients include gastrointestinal symptoms, a short period of relative stability, Cardiogenic shock, liver failure, and scarring of the gastrointestinal tract. Iron tablets are specifically tempting to children because they are similar to candy. Iron overdose in adults is usually to attempt suicide. Methods: The present study is a descriptive-analytic study based on hospital information, that was conducted among the patients affected with iron poisoning admitted to Razi hospital (a referral medical setting for poisoning treatment in southwest Iran) during 2014-2017. Patient information has been extracted and inserted in the inquiry form and data were analyzed by SPSS software. Results: In this study, 52 patients (94.2% female) were studied. 5 (9.6%) of women were pregnant.  The majority of them (69.2%) were between 15-25 years of age. Nausea and vomiting (50%) are two of the most common side effects. 5 patients (9.6%) received deferoxamine. All Patients who received deferoxamine, symptoms had less than 6 hours of onset. Most patients were hospitalized between 6-24 hours. 25% of patients took vitamins simultaneously with iron. The Serum level of iron in 3 patients (5.8%) was above 300 µg/dL. Based on this research, mortality was reported in one patient. Conclusion: In this study, the prevalence of iron poisoning was examined based on demographic and clinical characteristics. Considering the most prevalent iron poisoning in the young age group (96.2% suicides), more research in the psychological and social problems is critical for preventative behaviors.
first_indexed 2024-12-11T01:59:54Z
format Article
id doaj.art-936ee9b8bee140d7a4d9aafd23e2ebf2
institution Directory Open Access Journal
issn 2322-2611
2322-4320
language English
last_indexed 2024-12-11T01:59:54Z
publishDate 2020-09-01
publisher Mashhad University of Medical Sciences
record_format Article
series Asia Pacific Journal of Medical Toxicology
spelling doaj.art-936ee9b8bee140d7a4d9aafd23e2ebf22022-12-22T01:24:31ZengMashhad University of Medical SciencesAsia Pacific Journal of Medical Toxicology2322-26112322-43202020-09-019310211110.22038/apjmt.2020.1675116751Prevalence of symptoms in patients poisoned with iron in Ahvaz Razi Hospital in 2014-2017Ali hassan Rahmani0Shahrzad Molavinia1Fatemeh Boustani2Department of Clinical Toxicology, Razi Hospital, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranDepartment of Pharmacology and Toxicology, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranSchool of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranBackground: Iron is an important element for normal cell metabolism, but in excess amounts is quite cytotoxic, and even deadly. Iron poisoning is a calamity repeated many times in the world. The clinical signs of the patients include gastrointestinal symptoms, a short period of relative stability, Cardiogenic shock, liver failure, and scarring of the gastrointestinal tract. Iron tablets are specifically tempting to children because they are similar to candy. Iron overdose in adults is usually to attempt suicide. Methods: The present study is a descriptive-analytic study based on hospital information, that was conducted among the patients affected with iron poisoning admitted to Razi hospital (a referral medical setting for poisoning treatment in southwest Iran) during 2014-2017. Patient information has been extracted and inserted in the inquiry form and data were analyzed by SPSS software. Results: In this study, 52 patients (94.2% female) were studied. 5 (9.6%) of women were pregnant.  The majority of them (69.2%) were between 15-25 years of age. Nausea and vomiting (50%) are two of the most common side effects. 5 patients (9.6%) received deferoxamine. All Patients who received deferoxamine, symptoms had less than 6 hours of onset. Most patients were hospitalized between 6-24 hours. 25% of patients took vitamins simultaneously with iron. The Serum level of iron in 3 patients (5.8%) was above 300 µg/dL. Based on this research, mortality was reported in one patient. Conclusion: In this study, the prevalence of iron poisoning was examined based on demographic and clinical characteristics. Considering the most prevalent iron poisoning in the young age group (96.2% suicides), more research in the psychological and social problems is critical for preventative behaviors.https://apjmt.mums.ac.ir/article_16751_349d6de1217faadd1eab6a3e10158765.pdfpoisoningirondeferoxamine
spellingShingle Ali hassan Rahmani
Shahrzad Molavinia
Fatemeh Boustani
Prevalence of symptoms in patients poisoned with iron in Ahvaz Razi Hospital in 2014-2017
Asia Pacific Journal of Medical Toxicology
poisoning
iron
deferoxamine
title Prevalence of symptoms in patients poisoned with iron in Ahvaz Razi Hospital in 2014-2017
title_full Prevalence of symptoms in patients poisoned with iron in Ahvaz Razi Hospital in 2014-2017
title_fullStr Prevalence of symptoms in patients poisoned with iron in Ahvaz Razi Hospital in 2014-2017
title_full_unstemmed Prevalence of symptoms in patients poisoned with iron in Ahvaz Razi Hospital in 2014-2017
title_short Prevalence of symptoms in patients poisoned with iron in Ahvaz Razi Hospital in 2014-2017
title_sort prevalence of symptoms in patients poisoned with iron in ahvaz razi hospital in 2014 2017
topic poisoning
iron
deferoxamine
url https://apjmt.mums.ac.ir/article_16751_349d6de1217faadd1eab6a3e10158765.pdf
work_keys_str_mv AT alihassanrahmani prevalenceofsymptomsinpatientspoisonedwithironinahvazrazihospitalin20142017
AT shahrzadmolavinia prevalenceofsymptomsinpatientspoisonedwithironinahvazrazihospitalin20142017
AT fatemehboustani prevalenceofsymptomsinpatientspoisonedwithironinahvazrazihospitalin20142017