Organophosphorus Chemistry: Synthesis of New Phosphonic Acid Derivatives Bearing a Triazole Moiety
A series of new 1,2,3-triazolylphosphonates were synthesized through multicomponent alkyne-azide 1,3-dipolar cycloaddition catalyzed by copper nanoparticles on activated carbon. The reactions were carried out in water and at a very low copper loading as green conditions, leading to the triazolylphos...
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MDPI AG
2022-11-01
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Online Access: | https://www.mdpi.com/2673-4583/12/1/9 |
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author | Esteban Bjerg Joaquín Marchán-García Gabriel Radivoy Yanina Moglie Eduardo Buxaderas |
author_facet | Esteban Bjerg Joaquín Marchán-García Gabriel Radivoy Yanina Moglie Eduardo Buxaderas |
author_sort | Esteban Bjerg |
collection | DOAJ |
description | A series of new 1,2,3-triazolylphosphonates were synthesized through multicomponent alkyne-azide 1,3-dipolar cycloaddition catalyzed by copper nanoparticles on activated carbon. The reactions were carried out in water and at a very low copper loading as green conditions, leading to the triazolylphosphonate products in moderate to good yields. Studies into their activity as butyrylcholinesterase inhibitors are underway. |
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id | doaj.art-93708d1d53f448bba5e48e738762bc5f |
institution | Directory Open Access Journal |
issn | 2673-4583 |
language | English |
last_indexed | 2024-03-11T02:38:03Z |
publishDate | 2022-11-01 |
publisher | MDPI AG |
record_format | Article |
series | Chemistry Proceedings |
spelling | doaj.art-93708d1d53f448bba5e48e738762bc5f2023-11-18T09:47:43ZengMDPI AGChemistry Proceedings2673-45832022-11-01121910.3390/ecsoc-26-13585Organophosphorus Chemistry: Synthesis of New Phosphonic Acid Derivatives Bearing a Triazole MoietyEsteban Bjerg0Joaquín Marchán-García1Gabriel Radivoy2Yanina Moglie3Eduardo Buxaderas4Departamento de Química, INQUISUR-CONICET, Universidad Nacional del Sur, Av. Alem 1253, Bahía Blanca B8000CPB, ArgentinaDepartamento de Química, INQUISUR-CONICET, Universidad Nacional del Sur, Av. Alem 1253, Bahía Blanca B8000CPB, ArgentinaDepartamento de Química, INQUISUR-CONICET, Universidad Nacional del Sur, Av. Alem 1253, Bahía Blanca B8000CPB, ArgentinaDepartamento de Química, INQUISUR-CONICET, Universidad Nacional del Sur, Av. Alem 1253, Bahía Blanca B8000CPB, ArgentinaDepartamento de Química, INQUISUR-CONICET, Universidad Nacional del Sur, Av. Alem 1253, Bahía Blanca B8000CPB, ArgentinaA series of new 1,2,3-triazolylphosphonates were synthesized through multicomponent alkyne-azide 1,3-dipolar cycloaddition catalyzed by copper nanoparticles on activated carbon. The reactions were carried out in water and at a very low copper loading as green conditions, leading to the triazolylphosphonate products in moderate to good yields. Studies into their activity as butyrylcholinesterase inhibitors are underway.https://www.mdpi.com/2673-4583/12/1/9phosphonatestriazolecopper nanoparticles |
spellingShingle | Esteban Bjerg Joaquín Marchán-García Gabriel Radivoy Yanina Moglie Eduardo Buxaderas Organophosphorus Chemistry: Synthesis of New Phosphonic Acid Derivatives Bearing a Triazole Moiety Chemistry Proceedings phosphonates triazole copper nanoparticles |
title | Organophosphorus Chemistry: Synthesis of New Phosphonic Acid Derivatives Bearing a Triazole Moiety |
title_full | Organophosphorus Chemistry: Synthesis of New Phosphonic Acid Derivatives Bearing a Triazole Moiety |
title_fullStr | Organophosphorus Chemistry: Synthesis of New Phosphonic Acid Derivatives Bearing a Triazole Moiety |
title_full_unstemmed | Organophosphorus Chemistry: Synthesis of New Phosphonic Acid Derivatives Bearing a Triazole Moiety |
title_short | Organophosphorus Chemistry: Synthesis of New Phosphonic Acid Derivatives Bearing a Triazole Moiety |
title_sort | organophosphorus chemistry synthesis of new phosphonic acid derivatives bearing a triazole moiety |
topic | phosphonates triazole copper nanoparticles |
url | https://www.mdpi.com/2673-4583/12/1/9 |
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