SIRPα - CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen.

SIRPα - CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen.

The SIRPα-CD47 axis plays an important role in T cell recruitment to sites of immune reaction and inflammation but its role in T cell antigen priming is incompletely understood. Employing OTII TCR transgenic mice bred to Cd47-/- (Cd47KO) or SKI mice, a knock-in transgenic animal expressing non-signa...

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Huvudupphovsmän: Anu Autio, Huan Wang, Francisco Velázquez, Gail Newton, Charles A Parkos, Pablo Engel, Daniel Engelbertsen, Andrew H Lichtman, Francis W Luscinskas
Materialtyp: Artikel
Språk:English
Publicerad: Public Library of Science (PLoS) 2022-01-01
Serie:PLoS ONE
Länkar:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0266566&type=printable

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