One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines
Novel 1H-pyrimido [4,5-c][1,2]diazepines 3 & 4 and pyrazolo [3,4-d]pyrimidines 6 were regioselectively synthesised by the reaction of 1,3-dimethyl-6-hydrazinouracils 1 with various α,β-unsaturated compounds 2 and α-ketoalkynes 8 in excellent yields.
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Beilstein-Institut
2006-03-01
|
| Series: | Beilstein Journal of Organic Chemistry |
| Online Access: | https://doi.org/10.1186/1860-5397-2-5 |
| _version_ | 1818445020332556288 |
|---|---|
| author | Dipak Prajapati Partha P. Baruah Baikuntha J. Gogoi Jagir S. Sandhu |
| author_facet | Dipak Prajapati Partha P. Baruah Baikuntha J. Gogoi Jagir S. Sandhu |
| author_sort | Dipak Prajapati |
| collection | DOAJ |
| description | Novel 1H-pyrimido [4,5-c][1,2]diazepines 3 & 4 and pyrazolo [3,4-d]pyrimidines 6 were regioselectively synthesised by the reaction of 1,3-dimethyl-6-hydrazinouracils 1 with various α,β-unsaturated compounds 2 and α-ketoalkynes 8 in excellent yields. |
| first_indexed | 2024-12-14T19:25:11Z |
| format | Article |
| id | doaj.art-937448c6a5db420ca55b05e550078ea3 |
| institution | Directory Open Access Journal |
| issn | 1860-5397 |
| language | English |
| last_indexed | 2024-12-14T19:25:11Z |
| publishDate | 2006-03-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj.art-937448c6a5db420ca55b05e550078ea32022-12-21T22:50:12ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972006-03-0121510.1186/1860-5397-2-51860-5397-2-5One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidinesDipak Prajapati0Partha P. Baruah1Baikuntha J. Gogoi2Jagir S. Sandhu3Department of Medicinal Chemistry, Regional Research Laboratory, Jorhat 785006, Assam, IndiaDepartment of Medicinal Chemistry, Regional Research Laboratory, Jorhat 785006, Assam, IndiaDepartment of Medicinal Chemistry, Regional Research Laboratory, Jorhat 785006, Assam, IndiaDepartment of Chemistry, Panjabi University, Patiala 147 002, Punjab, IndiaNovel 1H-pyrimido [4,5-c][1,2]diazepines 3 & 4 and pyrazolo [3,4-d]pyrimidines 6 were regioselectively synthesised by the reaction of 1,3-dimethyl-6-hydrazinouracils 1 with various α,β-unsaturated compounds 2 and α-ketoalkynes 8 in excellent yields.https://doi.org/10.1186/1860-5397-2-5 |
| spellingShingle | Dipak Prajapati Partha P. Baruah Baikuntha J. Gogoi Jagir S. Sandhu One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines Beilstein Journal of Organic Chemistry |
| title | One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines |
| title_full | One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines |
| title_fullStr | One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines |
| title_full_unstemmed | One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines |
| title_short | One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines |
| title_sort | one pot synthesis of novel 1h pyrimido 4 5 c 1 2 diazepines and pyrazolo 3 4 d pyrimidines |
| url | https://doi.org/10.1186/1860-5397-2-5 |
| work_keys_str_mv | AT dipakprajapati onepotsynthesisofnovel1hpyrimido45c12diazepinesandpyrazolo34dpyrimidines AT parthapbaruah onepotsynthesisofnovel1hpyrimido45c12diazepinesandpyrazolo34dpyrimidines AT baikunthajgogoi onepotsynthesisofnovel1hpyrimido45c12diazepinesandpyrazolo34dpyrimidines AT jagirssandhu onepotsynthesisofnovel1hpyrimido45c12diazepinesandpyrazolo34dpyrimidines |