Restored CD8+PD-1+ T Cells Facilitate the Response to Anti-PD-1 for Patients With Pancreatic Ductal Adenocarcinoma

Restored CD8+PD-1+ T Cells Facilitate the Response to Anti-PD-1 for Patients With Pancreatic Ductal Adenocarcinoma

PurposeWe aimed to investigate the restoration of CD8+PD-1+ T cells through adoptive T-cell therapy (ACT) in relation to the prognosis and the therapeutic response to anti-PD-1 in patients with advanced pancreatic cancer (APC).MethodsA total of 177 adult patients who underwent tumor resection as ini...

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Bibliographic Details
Main Authors: Qian Zhu, Guoliang Qiao, Lefu Huang, Chang Xu, Deliang Guo, Shuo Wang, Jing Zhao, Yuguang Song, Bing Liu, Zheng Chen, Zhiyong Yang, Yufeng Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
CD8+PD-1+ T cell
TCR
PDAC
tumor resection
adoptive cell immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.837560/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.837560/full

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