Cerebrovascular events in COVID-19 patients

Neurological manifestations in patients with COVID–19 are more frequently being reported. Cerebrovascular events have been reported in around 3% of patients. In this review we summarize the published literature on cerebrovascular events in patients with COVID-19 as available on the PubMed database....

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Main Authors: Ajay Kumar Mishra, Kamal Kant Sahu, Anu Anna George, Jennifer Sargent, Amos Lal
Format: Article
Language:English
Published: PAGEPress Publications 2020-06-01
Series:Monaldi Archives for Chest Disease
Subjects:
Online Access:https://monaldi-archives.org/index.php/macd/article/view/1341
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author Ajay Kumar Mishra
Kamal Kant Sahu
Anu Anna George
Jennifer Sargent
Amos Lal
author_facet Ajay Kumar Mishra
Kamal Kant Sahu
Anu Anna George
Jennifer Sargent
Amos Lal
author_sort Ajay Kumar Mishra
collection DOAJ
description Neurological manifestations in patients with COVID–19 are more frequently being reported. Cerebrovascular events have been reported in around 3% of patients. In this review we summarize the published literature on cerebrovascular events in patients with COVID-19 as available on the PubMed database. So far, 3 studies have reported cerebrovascular events. Cerebrovascular events were identified on screening patients with decreased consciousness or in the presence of focal neurological deficits. These events were common in elderly, critically ill patients and in patients with prior cardio-cerebrovascular comorbidities. The diagnosis of cerebrovascular events was confirmed with computed tomography of the brain in most studies reporting neurological events. Multiple pathological mechanisms have been postulated regarding the process of neurological and vascular injury among which cytokine storm is shown to correlate with mortality. Patients with severe illness are found to have a higher cardio- cerebrovascular comorbidity. With an increasing number of cases and future prospective studies, the exact mechanism by which these cerebrovascular events occur and attribute to the poor outcome will be better understood.
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spelling doaj.art-937815135a044fa98eff12f835bfacf22022-12-22T03:18:05ZengPAGEPress PublicationsMonaldi Archives for Chest Disease1122-06432532-52642020-06-0190210.4081/monaldi.2020.1341Cerebrovascular events in COVID-19 patientsAjay Kumar Mishra0Kamal Kant Sahu1Anu Anna George2Jennifer Sargent3Amos Lal4Department of Internal Medicine, St. Vincent Hospital, Worcester, MADepartment of Internal Medicine, St. Vincent Hospital, Worcester, MADepartment of Internal Medicine, St. Vincent Hospital, Worcester, MADepartment of Internal Medicine, St. Vincent Hospital, Worcester; University of Massachusetts Medical School, Worcester, MADepartment of Internal Medicine, Division of Pulmonology and Critical Care Medicine, Mayo Clinic, Rochester, MNNeurological manifestations in patients with COVID–19 are more frequently being reported. Cerebrovascular events have been reported in around 3% of patients. In this review we summarize the published literature on cerebrovascular events in patients with COVID-19 as available on the PubMed database. So far, 3 studies have reported cerebrovascular events. Cerebrovascular events were identified on screening patients with decreased consciousness or in the presence of focal neurological deficits. These events were common in elderly, critically ill patients and in patients with prior cardio-cerebrovascular comorbidities. The diagnosis of cerebrovascular events was confirmed with computed tomography of the brain in most studies reporting neurological events. Multiple pathological mechanisms have been postulated regarding the process of neurological and vascular injury among which cytokine storm is shown to correlate with mortality. Patients with severe illness are found to have a higher cardio- cerebrovascular comorbidity. With an increasing number of cases and future prospective studies, the exact mechanism by which these cerebrovascular events occur and attribute to the poor outcome will be better understood.https://monaldi-archives.org/index.php/macd/article/view/1341COVID-19cerebrovascular eventsimagingmechanismoutcome
spellingShingle Ajay Kumar Mishra
Kamal Kant Sahu
Anu Anna George
Jennifer Sargent
Amos Lal
Cerebrovascular events in COVID-19 patients
Monaldi Archives for Chest Disease
COVID-19
cerebrovascular events
imaging
mechanism
outcome
title Cerebrovascular events in COVID-19 patients
title_full Cerebrovascular events in COVID-19 patients
title_fullStr Cerebrovascular events in COVID-19 patients
title_full_unstemmed Cerebrovascular events in COVID-19 patients
title_short Cerebrovascular events in COVID-19 patients
title_sort cerebrovascular events in covid 19 patients
topic COVID-19
cerebrovascular events
imaging
mechanism
outcome
url https://monaldi-archives.org/index.php/macd/article/view/1341
work_keys_str_mv AT ajaykumarmishra cerebrovasculareventsincovid19patients
AT kamalkantsahu cerebrovasculareventsincovid19patients
AT anuannageorge cerebrovasculareventsincovid19patients
AT jennifersargent cerebrovasculareventsincovid19patients
AT amoslal cerebrovasculareventsincovid19patients